ReviewChemical Society reviews2013
Manipulating biological agents and cells in micro-scale volumes for applications in medicine.
Review in Chemical Society reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02824471 (Sickle Cell Disease), which is not on this map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sickle Cell Disease (SCD) Biochip': Towards a Simple and Reliable Way to Monitor Sickle Cell Disease
Who cites it
42 citing papers in PubMed.
- Exploring the limits of magnetic levitation: submicron particle separation and density profiling.Materials research express · 2025Article
- Next generation microfluidics: fulfilling the promise of lab-on-a-chip technologies.Lab on a chip · 2024Review
- Advances of medical nanorobots for future cancer treatments.Journal of hematology & oncology · 2023Review
- Somatic Cell Reprogramming for Nervous System Diseases: Techniques, Mechanisms, Potential Applications, and Challenges.Brain sciences · 2023Review
- Multi-omics analysis of magnetically levitated plasma biomolecules.Biosensors & bioelectronics · 2023Article
- Magnetic Microrobots Fabricated by Photopolymerization and Assembly.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Review of Bubble Applications in Microrobotics: Propulsion, Manipulation, and Assembly.Micromachines · 2022Review
- Optoelectronic manipulation of bio-droplets containing cells or macromolecules by active ferroelectric platforms.Biomedical optics express · 2021Article
- Reversible Design of Dynamic Assemblies at Small Scales.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2021Article
- Reconfigurable multifunctional ferrofluid droplet robots.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Medical Micro/Nanorobots in Precision Medicine.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Review
- Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress.Journal of clinical medicine · 2020Article
- 3D Bioprinting Stem Cell Derived Tissues.Cellular and molecular bioengineering · 2018Review
- Emerging technologies for home-based semen analysis.Andrology · 2018Review
- Hydrogel Encapsulation Facilitates Rapid-Cooling Cryopreservation of Stem Cell-Laden Core-Shell Microcapsules as Cell-Biomaterial Constructs.Advanced healthcare materials · 2017Article
- Paper-based analytical devices for clinical diagnosis: recent advances in the fabrication techniques and sensing mechanisms.Expert review of molecular diagnostics · 2017Review
- 3-D Microwell Array System for Culturing Virus Infected Tumor Cells.Scientific reports · 2016Article
- Constructing 3D heterogeneous hydrogels from electrically manipulated prepolymer droplets and crosslinked microgels.Science advances · 2016Article
- Paramagnetic Structures within a Microfluidic Channel for Enhanced Immunomagnetic Isolation and Surface Patterning of Cells.Scientific reports · 2016Article
- Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Recent technological advances provide new tools to manipulate cells and biological agents in micro/nano-liter volumes. With precise control over small volumes, the cell microenvironment and other biological agents can be bioengineered; interactions between cells and external stimuli can be monitored; and the fundamental mechanisms such as cancer metastasis and stem cell differentiation can be elucidated. Technological advances based on the principles of electrical, magnetic, chemical, optical, acoustic, and mechanical forces lead to novel applications in point-of-care diagnostics, regenerative medicine, in vitro drug testing, cryopreservation, and cell isolation/purification. In this review, we first focus on the underlying mechanisms of emerging examples for cell manipulation in small volumes targeting applications such as tissue engineering. Then, we illustrate how these mechanisms impact the aforementioned biomedical applications, discuss the associated challenges, and provide perspectives for further development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.