ArticleThe ISME journal2013
Exploring nucleo-cytoplasmic large DNA viruses in Tara Oceans microbial metagenomes.
Article in The ISME journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 1 of them a synthesis that pooled it.
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133 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advances in phage-host interaction prediction: in silico method enhances the development of phage therapies.Briefings in bioinformatics · 2024Pooled it
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- Mycodnaviridae is a clade of giant viruses that persistently infect zoosporic fungi.PLoS biology · 2026Article
- Biological Trajectory of Virophage Research and the Emergence of Marine Virophages: A Scoping Review.Viruses · 2026Article
- Genomic analysis ofVirus evolution · 2026Article
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- Haptophyte-infecting viruses change the genome condensing proteins of dinoflagellates.Communications biology · 2025Article
- 20 years of research on giant viruses.Npj viruses · 2025Review
- Genome-resolved year-round dynamics reveal a broad range of giant virus microdiversity.mSystems · 2025Article
- Environmental gradients shape viral-host dynamics in the Pearl River estuary.ISME communications · 2025Article
- Phylogenetic proximity is a key driver of temporal succession of marine giant viruses in a five-year metagenomic time-series.ISME communications · 2025Article
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- Genomic and biogeographic characterisation of the novel prasinovirus Mantoniella tinhauana virus 1.Environmental microbiology reports · 2024Article
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- Assessing patterns of metazoans in the global ocean using environmental DNA.Royal Society open science · 2024Article
- Unraveling the habitat preferences, ecological drivers, potential hosts, and auxiliary metabolism of soil giant viruses across China.Microbiome · 2024Article
- Functional vertical connectivity of microbial communities in the ocean.Science advances · 2024Article
73 more citing papers are in PubMed but not listed here.
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25 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Nucleo-cytoplasmic large DNA viruses (NCLDVs) constitute a group of eukaryotic viruses that can have crucial ecological roles in the sea by accelerating the turnover of their unicellular hosts or by causing diseases in animals. To better characterize the diversity, abundance and biogeography of marine NCLDVs, we analyzed 17 metagenomes derived from microbial samples (0.2-1.6 μm size range) collected during the Tara Oceans Expedition. The sample set includes ecosystems under-represented in previous studies, such as the Arabian Sea oxygen minimum zone (OMZ) and Indian Ocean lagoons. By combining computationally derived relative abundance and direct prokaryote cell counts, the abundance of NCLDVs was found to be in the order of 10(4)-10(5) genomes ml(-1) for the samples from the photic zone and 10(2)-10(3) genomes ml(-1) for the OMZ. The Megaviridae and Phycodnaviridae dominated the NCLDV populations in the metagenomes, although most of the reads classified in these families showed large divergence from known viral genomes. Our taxon co-occurrence analysis revealed a potential association between viruses of the Megaviridae family and eukaryotes related to oomycetes. In support of this predicted association, we identified six cases of lateral gene transfer between Megaviridae and oomycetes. Our results suggest that marine NCLDVs probably outnumber eukaryotic organisms in the photic layer (per given water mass) and that metagenomic sequence analyses promise to shed new light on the biodiversity of marine viruses and their interactions with potential hosts.
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