Evidence map›Paper›PMID 23575365›Full record

ReviewJournal of nanobiotechnology2013

Microtechnologies to fuel neurobiological research with nanometer precision.

Cecilia A Brunello, Ville Jokinen, Prasanna Sakha, Hideyuki Terazono, Fumimasa Nomura, Tomoyuki Kaneko, Sari E Lauri, Sami Franssila, Claudio Rivera, Kenji Yasuda and 1 more

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Genetics of Alcohol Use Disorder: A Role for Induced Pluripotent Stem Cells?Alcoholism, clinical and experimental research · 2018
    Review
  6. Article
  7. Compartmentalized Microfluidic Platforms: The Unrivaled Breakthrough of In Vitro Tools for Neurobiological Research.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Investigation of nerve injury through microfluidic devices.Journal of the Royal Society, Interface · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cecilia A BrunelloNeuroscience Center, University of Helsinki, P.O. Box 56, Viikinkaari 4, FI-00014, Helsinki, Finland.
Ville Jokinen
Prasanna Sakha
Hideyuki Terazono
Fumimasa Nomura
Tomoyuki Kaneko
Sari E Lauri
Sami Franssila
Claudio Rivera
Kenji Yasuda
Henri J Huttunen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interface between engineering and molecular life sciences has been fertile ground for advancing our understanding of complex biological systems. Engineered microstructures offer a diverse toolbox for cellular and molecular biologists to direct the placement of cells and small organisms, and to recreate biological functions in vitro: cells can be positioned and connected in a designed fashion, and connectivity and community effects of cells studied. Because of the highly polar morphology and finely compartmentalized functions of neurons, microfabricated cell culture systems and related on-chip technologies have become an important enabling platform for studying development, function and degeneration of the nervous system at the molecular and cellular level. Here we review some of the compartmentalization techniques developed so far to highlight how high-precision control of neuronal connectivity allows new approaches for studying axonal and synaptic biology.

Indexed as

NeurobiologyAnimalsAxonsCaenorhabditis elegansDrosophila melanogasterMicrofluidicsMicrotechnologyModels, AnimalNanotechnologyNeurons

Identifiers

PMID23575365
PMCPMC3636074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.