Evidence map›Paper›PMID 23575346›Full record

ReviewCirculation journal : official journal of the Japanese Circulation Society2013

Regulation of chromatin structure in the cardiovascular system.

Manuel Rosa-Garrido, Elaheh Karbassi, Emma Monte, Thomas M Vondriska

Open access · diamondAbstract readReview
In one paragraph

Review in Circulation journal : official journal of the Japanese Circulation Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Genetic networks governing heart development.Cold Spring Harbor perspectives in medicine · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manuel Rosa-GarridoDepartment of Anesthesiology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA.
Elaheh Karbassi
Emma Monte
Thomas M Vondriska

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Dynamics of Cardiac Nuclei in Heart DiseaseR01HL105699 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VONDRISKA, THOMAS M. · 2011 to 2025
$5.0M
Training in Molecular, Cellular &Integrative PhysiologyT32GM065823 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TIDBALL, JAMES G · 2003 to 2017
$2.1M
Systems Analysis of Cardiac Chromatin StructureR01HL115238 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VONDRISKA, THOMAS M. · 2012 to 2016
$1.9M
American Heart Association-American Stroke Association 13PRE14430015NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NHLBI NIH HHS HL105699NHLBI NIH HHS HL115238NHLBI NIH HHS R01 HL105699NHLBI NIH HHS R01 HL115238NIGMS NIH HHS T32 GM065823
6 · The paper itself

Abstract

It has been appreciated for some time that cardiovascular disease involves large-scale transcriptional changes in various cell types. What has become increasingly clear only in the past few years, however, is the role of chromatin remodeling in cardiovascular phenotypes in normal physiology, as well as in development and disease. This review summarizes the state of the chromatin field in terms of distinct mechanisms to regulate chromatin structure in vivo, identifying when these modes of regulation have been demonstrated in cardiovascular tissues. We describe areas in which a better understanding of chromatin structure is leading to new insights into the fundamental biology of cardiovascular disease.

Indexed as

Chromatin Assembly and DisassemblyAnimalsCardiovascular DiseasesCardiovascular SystemChromatinHumansChromatin

Identifiers

PMID23575346
PMCPMC3704339
OpenAlexW2060309330

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.