ReviewBiological reviews of the Cambridge Philosophical Society2013
The role of the circadian system in fractal neurophysiological control.
Review in Biological reviews of the Cambridge Philosophical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Progression of Dementia Assessed by Temporal Correlations of Physical Activity: Results From a 3.5-Year, Longitudinal Randomized Controlled Trial.Scientific reports · 2016Trial
- Wobble board instability enhances proactive postural control.Chaos, solitons, and fractals · 2025Article
- Beyond FITT: addressing density in understanding the dose-response relationships of physical activity with health-an example based on brain health.European journal of applied physiology · 2025Review
- Article
- Detecting the fractal physical activity pattern in aged adults with cerebral small vessel disease.Frontiers in aging neuroscience · 2025Article
- Chronotype, sleep quality, depression and pre-sleep rumination: A diary and actigraphy study.The European journal of neuroscience · 2024Article
- Delineating cognitive resilience using fractal regulation: Cross-sectional and longitudinal evidence from the Rush Memory and Aging Project.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- General spectral characteristics of human activity and its inherent scale-free fluctuations.Scientific reports · 2024Article
- Altered Motor Activity Patterns within 10-Minute Timescale Predict Incident Clinical Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2024Article
- Approaches for assessing circadian rest-activity patterns using actigraphy in cohort and population-based studies.Current sleep medicine reports · 2023Article
- Stride-to-Stride Fluctuations of Human Gait Are Affected By Chronobiology: An Exploratory Study.Advanced biology · 2023Article
- The fractal brain: scale-invariance in structure and dynamics.Cerebral cortex (New York, N.Y. : 1991) · 2023Review
- Computational Approaches and Tools as Applied to the Study of Rhythms and Chaos in Biology.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Morphological characterization of Etv2 vascular explants using fractal analysis and atomic force microscopy.Microvascular research · 2021Article
- Fractal biomarker of activity in patients with bipolar disorder.Psychological medicine · 2021Article
- Fractal motor activity regulation and sex differences in preclinical Alzheimer's disease pathology.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
- Sleep Network Deterioration as a Function of Dim-Light-At-Night Exposure Duration in a Mouse Model.Clocks & sleep · 2020Article
- Interaction between the progression of Alzheimer's disease and fractal degradation.Neurobiology of aging · 2019Article
- More random motor activity fluctuations predict incident frailty, disability, and mortality.Science translational medicine · 2019Article
- Emergence of a complex movement pattern in an unfamiliar food place by foraging ants.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Many neurophysiological variables such as heart rate, motor activity, and neural activity are known to exhibit intrinsic fractal fluctuations - similar temporal fluctuation patterns at different time scales. These fractal patterns contain information about health, as many pathological conditions are accompanied by their alteration or absence. In physical systems, such fluctuations are characteristic of critical states on the border between randomness and order, frequently arising from nonlinear feedback interactions between mechanisms operating on multiple scales. Thus, the existence of fractal fluctuations in physiology challenges traditional conceptions of health and disease, suggesting that high levels of integrity and adaptability are marked by complex variability, not constancy, and are properties of a neurophysiological network, not individual components. Despite the subject's theoretical and clinical interest, the neurophysiological mechanisms underlying fractal regulation remain largely unknown. The recent discovery that the circadian pacemaker (suprachiasmatic nucleus) plays a crucial role in generating fractal patterns in motor activity and heart rate sheds an entirely new light on both fractal control networks and the function of this master circadian clock, and builds a bridge between the fields of circadian biology and fractal physiology. In this review, we sketch the emerging picture of the developing interdisciplinary field of fractal neurophysiology by examining the circadian system's role in fractal regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.