ArticlePloS one2013
Patients with severe radiographic osteoarthritis have a better prognosis in physical functioning after hip and knee replacement: a cohort-study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03339557 (Functional Outcome of Total Knee Replacement. Randomized Clinical Controlled Trial of Novel and Conventional Implants), which is not on this map. Cited by 52 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Functional Outcome of Total Knee Replacement. Randomized Clinical Controlled Trial of Novel and Conventional Implants
Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Surgery for early structural osteoarthritis of the hip and knee: the SCORE evidence synthesis and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Mild radiographic osteoarthritis is associated with increased pain and dissatisfaction following total knee arthroplasty when compared with severe osteoarthritis: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Why are patients dissatisfied following a total knee replacement? A systematic review.International orthopaedics · 2020Pooled it
- Preoperative predictors for outcomes after total hip replacement in patients with osteoarthritis: a systematic review.BMC musculoskeletal disorders · 2016Pooled it
- Trial
- Predictors of response to prefabricated foot orthoses or rocker-sole footwear in individuals with first metatarsophalangeal joint osteoarthritis.BMC musculoskeletal disorders · 2017Trial
- The reason why orthopaedic surgeons perform total knee replacement: results of a randomised study using case vignettes.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016Trial
- Radiological pattern of hip osteoarthritis is associated with one-year patient-reported outcomes but not long-term mortality or revision after total hip arthroplasty : a retrospective case series.Bone & joint open · 2026Article
- Association between preoperative radiographic osteoarthritis severity and patient-reported outcomes after total hip arthroplasty: a systematic review and meta-analysis.International orthopaedics · 2026Review
- Influence of bone marrow lesions in the intercondylar eminence of tibia on postoperative outcomes after medial unicompartmental knee arthroplasty -a pilot study.BMC musculoskeletal disorders · 2026Article
- Predictive factors for forgotten joints after direct anterior approach total hip arthroplasty.BMC musculoskeletal disorders · 2026Article
- Pain-induced sleep disturbances fully mediate the association between symptomatic hip and knee osteoarthritis and poor sleep quality : a cross-sectional study.Bone & joint open · 2026Article
- Evaluating a semiquantitative magnetic resonance imaging-based scoring system to predict hip preservation or arthroplasty in patients with an intact preoperative joint space.Journal of hip preservation surgery · 2025Article
- Diagnostic injections are predictive of similar improvements following total hip arthroplasty in patients with radiologically mild osteoarthritis.Bone & joint open · 2025Article
- Can status of superficial medial collateral ligament proximal tibial attachment predict progression of OA knee?Journal of orthopaedics · 2024Article
- Factors to improve odds of success following medial opening-wedge high tibial osteotomy: a machine learning analysis.BMC musculoskeletal disorders · 2024Article
- Hospital variation in revision rates after primary knee arthroplasty was not explained by patient selection: baseline data from 1452 patients in the Danish prospective multicenter cohort study, SPARK.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Observational
- Less improvement in knee function and higher rates of dissatisfaction in the short-term following total knee arthroplasty in people with mild radiographic arthritis.Archives of orthopaedic and trauma surgery · 2023Article
- Mitochondrial function, grip strength, and activity are related to recovery of mobility after a total knee arthroplasty.Clinical and translational science · 2023Article
- Medial unicondylar knee arthroplasty should be reserved for patients with complete joint space collapse.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAlthough Total Hip and Knee Replacements (THR/TKR) improve Health-Related Quality of Life (HRQoL) at the group level, up to 30% of patients are dissatisfied after surgery due to unfulfilled expectations. We aimed to assess whether the pre-operative radiographic severity of osteoarthritis (OA) is related to the improvement in HRQoL after THR or TKR, both at the population and individual level.
methodsIn this multi-center observational cohort study, HRQoL of OA patients requiring THR or TKR was measured 2 weeks before surgery and at 2-5 years follow-up, using the Short-Form 36 (SF36). Additionally, we measured patient satisfaction on a 11-point Numeric Rating Scale (NRSS). The radiographic severity of OA was classified according to Kellgren and Lawrence (KL) by an independent experienced musculoskeletal radiologist, blinded for the outcome. We compared the mean improvement and probability of a relevant improvement (defined as a patients change score ≥ Minimal Clinically Important Difference) between patients with mild OA (KL Grade 0-2) and severe OA (KL Grade 3+4), whilst adjusting for confounders.
resultsSevere OA patients improved more and had a higher probability of a relevant improvement in physical functioning after both THR and TKR. For TKR patients with severe OA, larger improvements were found in General Health, Vitality and the Physical Component Summary Scale. The mean NRSS was also higher in severe OA TKR patients. DISCUSSION: Patients with severe OA have a better prognosis after THR and TKR than patients with mild OA. These findings might help to prevent dissatisfaction after THR and TKR by means of patient selection or expectation management.
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Registered trials
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