ArticleThe Plant cell2013
The classical arabinogalactan protein AGP18 mediates megaspore selection in Arabidopsis.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 106 citations in OpenAlex.
- Arabinogalactan Proteins in Pollen-Pistil Interactions: Molecular Regulators of Reproductive Barriers and Compatibility.International journal of molecular sciences · 2026Review
- Review
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- Basis of apomixis in flowering plants - state of the art and research perspectives.Plant reproduction · 2026Review
- Genome-Wide Identification and Classification of Arabinogalactan Proteins Gene Family inInternational journal of molecular sciences · 2025Article
- Developmental cues are encoded by the combinatorial phosphorylation of Arabidopsis RETINOBLASTOMA-RELATED protein RBR1.The EMBO journal · 2024Article
- Cell death in bryophytes: emerging models to study core regulatory modules and conserved pathways.Annals of botany · 2024Review
- Cluster effect through the oligomerisation of bioactive disaccharide AMOR on pollen tube capacitation inRSC chemical biology · 2024Article
- The miRNA822 loaded by ARGONAUTE9 modulates the monosporic female gametogenesis in Arabidopsis thaliana.Plant reproduction · 2024Article
- AGPs as molecular determinants of reproductive development.Annals of botany · 2023Article
- Mutation of DEFECTIVE EMBRYO SAC1 results in a low seed-setting rate in rice by regulating embryo sac development.Journal of experimental botany · 2023Article
- Arabinogalactan Proteins: Focus on the Role in Cellulose Synthesis and Deposition during Plant Cell Wall Biogenesis.International journal of molecular sciences · 2022Review
- New insights on the expression patterns of specific Arabinogalactan proteins in reproductive tissues ofFrontiers in plant science · 2022Article
- Links between Regulatory Systems of ROS and Carbohydrates in Reproductive Development.Plants (Basel, Switzerland) · 2021Review
- Article
- CRISPR-Cas9 multiplex genome editing of the hydroxyproline-O-galactosyltransferase gene family alters arabinogalactan-protein glycosylation and function in Arabidopsis.BMC plant biology · 2021Article
- Transcriptional Regulation and Signaling of Developmental Programmed Cell Death in Plants.Frontiers in plant science · 2021Review
- Arabinogalactan Proteins in Plant Roots - An Update on Possible Functions.Frontiers in plant science · 2021Review
- Bridging the GAPs in plant reproduction: a comparison of plant and animal GPI-anchored proteins.Plant reproduction · 2020Review
- The Transmembrane Protein Semi1 Positions Gamete Nuclei for Reciprocal Fertilization in Tetrahymena.iScience · 2020Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
Female gametogenesis in most flowering plants depends on the predetermined selection of a single meiotically derived cell, as the three other megaspores die without further division or differentiation. Although in Arabidopsis thaliana the formation of the functional megaspore (FM) is crucial for the establishment of the gametophytic generation, the mechanisms that determine the specification and fate of haploid cells remain unknown. Here, we show that the classical arabinogalactan protein 18 (AGP18) exerts an active regulation over the selection and survival of megaspores in Arabidopsis. During meiosis, AGP18 is expressed in integumentary cells located in the abaxial region of the ovule. Overexpression of AGP18 results in the abnormal maintenance of surviving megaspores that can acquire a FM identity but is not sufficient to induce FM differentiation before meiosis, indicating that AGP18 positively promotes the selection of viable megaspores. We also show that all four meiotically derived cells in the ovule of Arabidopsis are competent to differentiate into a gametic precursor and that the function of AGP18 is important for their selection and viability. Our results suggest an evolutionary role for arabinogalactan proteins in the acquisition of monospory and the developmental plasticity that is intrinsic to sexual reproduction in flowering plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.