ArticleThe Plant cell2013
Arabidopsis Sec1/Munc18 protein SEC11 is a competitive and dynamic modulator of SNARE binding and SYP121-dependent vesicle traffic.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Molecular choreography of vesicle trafficking: Exocyst-SNARE interplay in plant defense.Journal of advanced research · 2026Review
- A MAP-SNARE interaction links cortical microtubules to the exocytic fusion machinery during auxin-dependent growth remodeling.Science advances · 2026Article
- COJournal of integrative plant biology · 2026Article
- Article
- GORK KNature communications · 2025Article
- Dissecting genomic regions and candidate genes for pod borer resistance and component traits in pigeonpea minicore collection.Frontiers in plant science · 2025Article
- SYNTAXIN OF PLANTS 132 underpins secretion of cargoes associated with salicylic acid signaling and pathogen defense.Plant physiology · 2024Article
- Endomembrane trafficking driven by microtubule growth regulates stomatal movement in Arabidopsis.Nature communications · 2024Article
- Genetic resources and genes/QTLs for gram pod borer (Helicoverpa armigera Hübner) resistance in chickpea from the Western Himalayas.The plant genome · 2024Article
- Roles of the ArabidopsisInternational journal of molecular sciences · 2024Article
- Synaptotagmin 4 and 5 additively contribute to Arabidopsis immunity toPlant signaling & behavior · 2022Article
- Engineering a KNature plants · 2022Article
- Arabidopsis HOPS subunit VPS41 carries out plant-specific roles in vacuolar transport and vegetative growth.Plant physiology · 2022Article
- SNARE SYP132 mediates divergent traffic of plasma membrane H+-ATPase AHA1 and antimicrobial PR1 during bacterial pathogenesis.Plant physiology · 2022Article
- SEC1A is a major Arabidopsis Sec1/Munc18 gene in vesicle trafficking during pollen tube tip growth.The Plant journal : for cell and molecular biology · 2022Article
- Genome-wide dynamic network analysis reveals the potential genes for MeJA-induced growth-to-defense transition.BMC plant biology · 2021Article
- Synaptotagmin 5 Controls SYP132-VAMP721/722 Interaction for Arabidopsis Immunity toMolecules and cells · 2021Article
- The Arabidopsis R-SNARE VAMP714 is essential for polarisation of PIN proteins and auxin responses.The New phytologist · 2021Article
- Tri-SUS: a yeast split-ubiquitin assay to examine protein interactions governed by a third binding partner.Plant physiology · 2021Article
- Integrative Proteomic and Phosphoproteomic Analyses of Pattern- and Effector-Triggered Immunity in Tomato.Frontiers in plant science · 2021Article
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9 authors.
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Abstract
The Arabidopsis thaliana Qa-SNARE SYP121 (=SYR1/PEN1) drives vesicle traffic at the plasma membrane of cells throughout the vegetative plant. It facilitates responses to drought, to the water stress hormone abscisic acid, and to pathogen attack, and it is essential for recovery from so-called programmed stomatal closure. How SYP121-mediated traffic is regulated is largely unknown, although it is thought to depend on formation of a fusion-competent SNARE core complex with the cognate partners VAMP721 and SNAP33. Like SYP121, the Arabidopsis Sec1/Munc18 protein SEC11 (=KEULE) is expressed throughout the vegetative plant. We find that SEC11 binds directly with SYP121 both in vitro and in vivo to affect secretory traffic. Binding occurs through two distinct modes, one requiring only SEC11 and SYP121 and the second dependent on assembly of a complex with VAMP721 and SNAP33. SEC11 competes dynamically for SYP121 binding with SNAP33 and VAMP721, and this competition is predicated by SEC11 association with the N terminus of SYP121. These and additional data are consistent with a model in which SYP121-mediated vesicle fusion is regulated by an unusual "handshaking" mechanism of concerted SEC11 debinding and rebinding. They also implicate one or more factors that alter or disrupt SEC11 association with the SYP121 N terminus as an early step initiating SNARE complex formation.
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