ArticleGenome biology and evolution2013
Gene conversion shapes linear mitochondrial genome architecture.
Article in Genome biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Evolution and maintenance of mtDNA gene content across eukaryotes.The Biochemical journal · 2024Review
- Intermolecular Gene Conversion for the Equalization of Genome Copies in the Polyploid HaloarchaeonGenes · 2024Article
- Characterization of the complete mitochondrial genome of Miamiensis avidus causing flatfish scuticociliatosis.Genetica · 2022Article
- Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome.BMC biology · 2021Article
- Mitochondrial Genomic Landscape: A Portrait of the Mitochondrial Genome 40 Years after the First Complete Sequence.Life (Basel, Switzerland) · 2021Article
- Is the Dinoflagellate Amoebophrya Really Missing an mtDNA?Molecular biology and evolution · 2021Article
- A novel fragmented mitochondrial genome in the protist pathogenGenome research · 2021Article
- Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck.PLoS biology · 2021Article
- Multiple Independent Changes in Mitochondrial Genome Conformation in Chlamydomonadalean Algae.Genome biology and evolution · 2017Article
- The linear plastid chromosomes of maize: terminal sequences, structures, and implications for DNA replication.Current genetics · 2016Article
- Mitochondrial and plastid genome architecture: Reoccurring themes, but significant differences at the extremes.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- DNA maintenance in plastids and mitochondria of plants.Frontiers in plant science · 2015Review
- Horizontal transfer and gene conversion as an important driving force in shaping the landscape of mitochondrial introns.G3 (Bethesda, Md.) · 2014Article
- Fast-evolving mitochondrial DNA in Ceriantharia: a reflection of hexacorallia paraphyly?PloS one · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, it was shown that gene conversion between the ends of linear mitochondrial chromosomes can cause telomere expansion and the duplication of subtelomeric loci. However, it is not yet known how widespread this phenomenon is and how significantly it has impacted organelle genome architecture. Using linear mitochondrial DNAs and mitochondrial plasmids from diverse eukaryotes, we argue that telomeric recombination has played a major role in fashioning linear organelle chromosomes. We find that mitochondrial telomeres frequently expand into subtelomeric regions, resulting in gene duplications, homogenizations, and/or fragmentations. We suggest that these features are a product of subtelomeric gene conversion, provide a hypothetical model for this process, and employ genetic diversity data to support the idea that the greater the effective population size the greater the potential for gene conversion between subtelomeric loci.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.