Evidence map›Paper›PMID 23572221›Full record

ArticleSurgical endoscopy2013

Prospective evaluation of pain control and quality of life in patients with chronic pancreatitis following bilateral thoracoscopic splanchnicectomy.

Malgorzata B Malec-Milewska, Wieslaw Tarnowski, Adam E Ciesielski, Emilia Michalik, Maciej R Guc, Jacek A Jastrzebski

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Surgical endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03117556 (Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03117556 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

Bilateral Thoracoscopic Splanchnicectomy for Pain Relief in Patients With Unresectable Pancreatic Cancer

TypeinterventionalSponsorUniversity of LouisvilleRan2017 to 2018Enrolled0ConditionsUnresectable Pancreatic CancerArmsBilateral Thoracoscopic Splanchnicectomy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Treatment options in painful chronic pancreatitis: a systematic review.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2014
    Pooled it
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Malgorzata B Malec-MilewskaDepartment of Anesthesiology and Intensive Care, Medical Center for Postgraduate Education, Ul. Czerniakowska 231, 00-416, Warsaw, Poland, lmilewski@post.pl.
Wieslaw Tarnowski
Adam E Ciesielski
Emilia Michalik
Maciej R Guc
Jacek A Jastrzebski
Postgraduate School of Molecular Medicine · PLPolish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbdominal pain in chronic pancreatitis (CP) is the most common symptom with a highly unfavorable impact on the quality of life. It has been shown that bilateral thoracoscopic splanchnicectomy (BTS) may produce marked pain relief for the majority of patients. The aim of this study was to evaluate the effectiveness of BTS in pain control and quality-of-life improvement in patients with a severe form of CP.

methodsBetween April 2000 and April 2009, a total of 30 patients qualified for BTS due to CP-related pain. Their age ranged from 28 to 60 years. A 12-month follow-up period was planned for all the patients enrolled. To evaluate effectiveness of BTS, an 11-point Numeric Rating Scale (NRS) and the Quality of Life Questionnaire C-30 (QLQ-C30) in its basic form, developed by European Organization for Research and Treatment of Cancer, were used. An NRS value between 0 and 3 was considered a positive postoperative pain control result.

resultsThe bilateral splanchnicectomy procedure was performed successfully in 27 of 30 qualified patients. A positive effect based on decreased pain (p < 0.05) at 12 months was achieved in 24 patients (80 %). The initial change in quality of life was not significant but it gradually improved with time (preop vs. 12 months QLQ-C30 score, p < 0.001).

conclusionsThis study showed that BTS is safe and efficacious for pain alleviation in patients with severe CP. It may significantly increase the chances of a long-lasting, life-changing improvement in the quality of life.

Indexed as

Autonomic DenervationPain ManagementQuality of LifeAbdominal PainAdultFemaleHumansIntractable PainMaleMiddle AgedPancreatitis, AlcoholicPancreatitis, ChronicProspective StudiesSplanchnic NervesThoracoscopy

Identifiers

PMID23572221
PMCPMC3771415
OpenAlexW2051030700

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.