ArticleSurgical endoscopy2013
A pilot study of natural orifice transanal endoscopic total mesorectal excision with laparoscopic assistance for rectal cancer.
Article in Surgical endoscopy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01340755 (A Pilot Study of Laparoscopy-Assisted Transanal Endoscopy Rectosigmoid Resection for Rectal Cancer), which is not on this map. Cited by 55 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot Study of Laparoscopy-Assisted Transanal Endoscopy Rectosigmoid Resection for Rectal Cancer
Who cites it
55 citing papers in PubMed, 6 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Comparison of oncological and functional outcomes and quality of life after transanal or laparoscopic total mesorectal excision for rectal cancer: a systematic review and meta-analysis.Techniques in coloproctology · 2021Pooled it
- Clinical outcomes and case volume effect of transanal total mesorectal excision for rectal cancer: a systematic review.Techniques in coloproctology · 2016Pooled it
- Transanal total mesorectal excision for rectal cancer: a single center experience and systematic review of the literature.Langenbeck's archives of surgery · 2015Pooled it
- Transanal total mesorectal excision: a systematic review of the experimental and clinical evidence.Techniques in coloproctology · 2015Pooled it
- Laparoscopic natural orifice specimen extraction-colectomy: a systematic review.World journal of gastroenterology · 2014Pooled it
- A systematic review of transanal minimally invasive surgery (TAMIS) from 2010 to 2013.Techniques in coloproctology · 2014Pooled it
- Potential sexual function improvement by using transanal mesorectal approach for laparoscopic low rectal cancer excision.Surgical endoscopy · 2016Trial
- Phase II clinical experience and long-term follow-up using the next-generation single-incision platform FMX314.Surgical endoscopy · 2016Trial
- Article
- Comparison of transanal total mesorectal excision and robotic total mesorectal excision for rectal cancer: an inverse probability of treatment weighting analysis.World journal of surgical oncology · 2025Article
- Article
- Anorectal and urogenital functional outcome after robotic and transanal total mesorectal excision for rectal cancer: a propensity score-matched analysis.Techniques in coloproctology · 2025Article
- Short-term and long-term survival outcomes for transrectal specimen extraction after laparoscopic right hemicolectomy: a propensity-score matching study.Frontiers in oncology · 2023Article
- Education and Training in Transanal Endoscopic Surgery and Transanal Total Mesorectal Excision.Clinics in colon and rectal surgery · 2021Review
- Transanal total mesorectal excision (taTME) for rectal cancer: beyond the learning curve.Surgical endoscopy · 2020Article
- The Efficacy of Transanal Total Mesorectal Excision: a Preliminary Vietnamese Report.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2020Article
- Evolution of Transanal Total Mesorectal Excision.Clinics in colon and rectal surgery · 2020Review
- Transanal Total Proctocolectomy with Ileal Pouch-Anal Anastomosis for Synchronous Triple Colorectal Cancer.Journal of laparoendoscopic & advanced surgical techniques. Part B, Videoscopy · 2019Article
- Transanal total mesorectal excision (TaTME): current status and future perspectives.Updates in surgery · 2019Review
- Comparison of short-term and survival outcomes for transanal natural orifice specimen extraction with conventional mini-laparotomy after laparoscopic anterior resection for colorectal cancer.Cancer management and research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this pilot study was to evaluate the feasibility and safety of natural orifice endoscopic transanal total mesorectal excision (TME) with laparoscopic assistance in a cohort study of five patients with stage I and IIA rectal cancer.
methodsFive eligible patients with node-negative rectal cancer located 4-12 cm from the anal verge were enrolled in an IRB-approved pilot study. All patients underwent transanal endoscopic TME with laparoscopic assistance, hand-sewn coloanal anastomosis, and a diverting loop ileostomy. Primary and secondary end points included adequacy of the mesorectal excision and 30-day postoperative complications, respectively.
resultsBetween November 2011 and May 2012, three males and two females underwent transanal endoscopic TME with laparoscopic assistance. Patient mean age and BMI were 48.6 ± 9.8 years and 25.7 ± 2.3 kg/m(2), respectively. Tumors were located an average of 5.7 ± 2.4 cm from the anal verge and preoperatively staged as T1N0M0 (2), T2N0M0 (1), and T3N0M0 (2). Mean operative time was 274.6 ± 85.4 min with no intraoperative complications. Partial intersphincteric resection was performed in conjunction with transanal endoscopic TME in three patients. Pathologic examination of TME specimens demonstrated complete mesorectal excision in all cases with negative proximal, distal, and radial margins. Mean length of hospital stay was 5.2 ± 2.6 days and three minor complications occurred, including one ileus and two cases of transient urinary dysfunction. At a mean early follow-up of 5.4 ± 2.3 months, all patients remain disease-free.
conclusionsIn this pilot study of five patients with rectal cancer, transanal endoscopic TME with laparoscopic assistance is feasible and safe, and is a promising alternative to open and laparoscopic TME. Evaluation of long-term functional and oncologic outcomes of this approach is needed before widespread adoption can be recommended.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.