Evidence map›Paper›PMID 23572012›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2013

Dose-response associations between number and frequency of substance use and high-risk sexual behaviors among HIV-negative substance-using men who have sex with men (SUMSM) in San Francisco.

Glenn-Milo Santos, Phillip O Coffin, Moupali Das, Tim Matheson, Erin DeMicco, Jerris L Raiford, Eric Vittinghoff, James W Dilley, Grant Colfax, Jeffrey H Herbst

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01279044 phase1 / phase2completednot on this map

Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM): Adaptation of the Personalized Cognitive Counseling (PCC) Intervention

TypeinterventionalSponsorSan Francisco Department of Public HealthRan2007 to 2012Enrolled385ConditionsHIV Infections, Episodic Substance UseArmsAdapted Personalized Cognitive Risk-reduction Counseling intervention (PCC), Standard HIV testing with information only
NCT03192995 phase2terminatednot on this mapstarted 2018, after this paper: background citation

Treatment With Lorcaserin for Cocaine Use: The TLC Study

TypeinterventionalSponsorGlenn-Milo SantosRan2018 to 2020Enrolled22ConditionsCocaine Use DisorderArmslorcaserin, Placebo Oral Tablet, Substance use counseling, ACASI, Cocaine metabolites
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  18. Prediction Model for the Risk of HIV Infection among MSM in China: Validation and Stability.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Glenn-Milo SantosSan Francisco Department of Public Health, San Francisco, CA 94102, USA. glenn-milo.santos@sfdph.org
Phillip O Coffin
Moupali Das
Tim Matheson
Erin DeMicco
Jerris L Raiford
Eric Vittinghoff
James W Dilley
Grant Colfax
Jeffrey H Herbst

Funding

Reducing HIV risk among episodic substance-using MSMUR6PS000684 · PS · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI COFFIN, PHILLIP O · 2007 to 2011
$1.8M
Intramural CDC HHS CC999999NCHHSTP CDC HHS UR6 PS000684NCHHSTP CDC HHS UR6PS000684
6 · The paper itself

Abstract

We evaluated the relationship between frequency and number of substances used and HIV risk [ie, serodiscordant unprotected anal intercourse (SDUAI)] among 3173 HIV-negative substance-using MSM. Compared with nonusers, the adjusted odds ratio (AOR) for SDUAI among episodic and at least weekly users, respectively, was 3.31 [95% confidence interval (CI), 2.55 to 4.28] and 5.46 (95% CI, 3.80 to 7.84) for methamphetamine, 1.86 (95% CI, 1.51 to 2.29) and 3.13 (95% CI, 2.12 to 4.63) for cocaine, and 2.08 (95% CI, 1.68 to 2.56) and 2.54 (95% CI, 1.85 to 3.48) for poppers. Heavy alcohol drinkers reported more SDUAI than moderate drinkers [AOR, 1.90 (95% CI, 1.43 to 2.51)]. Compared with nonusers, AORs for using 1, 2, and ≥3 substances were 16.81 (95% CI, 12.25 to 23.08), 27.31 (95% CI, 18.93 to 39.39), and 46.38 (95% CI, 30.65 to 70.19), respectively. High-risk sexual behaviors were strongly associated with frequency and number of substances used.

Indexed as

HIV SeronegativityHomosexuality, MaleIllicit DrugsAdultAlcohol DrinkingCocaineConfidence IntervalsCross-Sectional StudiesHumansMaleMarijuana SmokingMethamphetamineNitratesOdds RatioPentanolsRisk-Takingamyl nitrateCocaineIllicit DrugsMethamphetamineNitratesPentanols

Identifiers

PMID23572012
PMCPMC4671496

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.