SynthesisIntensive care medicine2013
Noninvasive ventilation in chest trauma: systematic review and meta-analysis.
Synthesis in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 115 citations in OpenAlex.
- Use of a helmet for oxygen therapy in critically ill patients: a systematic review and meta-analysis.The Journal of international medical research · 2020Pooled it
- Brazilian recommendations of mechanical ventilation 2013. Part 2.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2014Guideline
- Noninvasive ventilation in adults with blunt chest trauma: A meta-analysis of randomized clinical trials.Brazilian journal of physical therapyPooled it
- Early non-invasive ventilation and high-flow nasal oxygen therapy for preventing endotracheal intubation in hypoxemic blunt chest trauma patients: the OptiTHO randomized trial.Critical care (London, England) · 2023Trial
- Noninvasive ventilation with a helmet in patients with acute respiratory failure caused by chest trauma: a randomized controlled trial.Scientific reports · 2020Trial
- Changing use of noninvasive ventilation in critically ill patients: trends over 15 years in francophone countries.Intensive care medicine · 2016Trial
- Complex perioperative and anaesthesia management of a polytrauma patient with intrathoracic haemorrhage undergoing emergency lobectomy.Trauma case reports · 2026Article
- Heterogeneity in Self-Reported Management of Blunt Chest Trauma: An International Cross-Sectional Survey.Journal of clinical medicine · 2026Article
- Effect of management in intermediate care unit versus conventional hospitalization on long-term mortality and autonomy in patients with rib fractures aged 75 years and older: a retrospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Observational
- Noninvasive ventilation in chest trauma-related acute respiratory failure related to chest trauma: Efficacy and risk of pneumothorax.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Problematic meta-analyses: Bayesian and frequentist perspectives on combining randomized controlled trials and non-randomized studies.BMC medical research methodology · 2024Article
- Risk factors affecting severe thoracic injuries in motor vehicle collisions based on age group and collision directions.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Observational
- C-reactive protein in the early diagnosis of pneumonia complicating severe blunt chest trauma.La Tunisie medicale · 2023Article
- Respiratory challenges and ventilatory management in different types of acute brain-injured patients.Critical care (London, England) · 2023Review
- In-Hospital Predictors of Need for Ventilatory Support and Mortality in Chest Trauma: A Multicenter Retrospective Study.Journal of clinical medicine · 2023Article
- Article
- Predictive Factors of Ventilatory Support in Chest Trauma.Life (Basel, Switzerland) · 2021Article
- Non-invasive ventilation in the ED: Whom, When, How?Turkish journal of emergency medicine · 2018Review
- Non-Invasive Mechanical Ventilation in Critically Ill Trauma Patients: A Systematic Review.Turkish journal of anaesthesiology and reanimation · 2018Review
- Severe thoracic trauma - still an independent predictor for death in multiple injured patients?Scandinavian journal of trauma, resuscitation and emergency medicine · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSingle studies of Noninvasive Ventilation (NIV) in the management of acute respiratory failure in chest trauma patients have produced controversial findings. The aim of this study is to critically review the literature to investigate whether NIV reduces mortality, intubation rate, length of stay and complications in patients with chest trauma, compared to standard therapy.
methodsWe performed a systematic review and meta-analysis of randomized controlled trials, prospective and retrospective observational studies, by searching PubMed, EMBASE and bibliographies of articles retrieved. We screened for relevance studies that enrolled adults with chest trauma who developed mild to severe acute respiratory failure and were treated with NIV. We included studies reporting at least one clinical outcome of interest to perform a meta-analysis.
resultsTen studies (368 patients) met the inclusion criteria and were included for the meta-analysis. Five studies (219 patients) reported mortality and results were quite homogeneous across studies, with a summary relative risk for patients treated with NIV compared with standard care (oxygen therapy and invasive mechanical ventilation) of 0.26 (95 % confidence interval 0.09-0.71, p = 0.003). There was no advantage in mortality of continuous positive airway pressure over noninvasive pressure support ventilation. NIV significantly increased arterial oxygenation and was associated with a significant reduction in intubation rate, in the incidence of overall complications and infections.
conclusionsThese results suggest that NIV could be useful in the management of acute respiratory failure due to chest trauma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.