Evidence map›Paper›PMID 23571528›Full record

ArticleMenopause (New York, N.Y.)2013

Sternal skin conductance: a reasonable surrogate for hot flash measurement?

Deirdre R Pachman, Charles L Loprinzi, Paul J Novotny, Daniel V Satele, Breanna M Linquist, Sherry Wolf, Debra L Barton

Abstract readHistorical Article
In one paragraph

Article in Menopause (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deirdre R PachmanFrom the 1Department of Oncology and 2Cancer Center Statistics, Mayo Clinic, Rochester, MN.
Charles L Loprinzi
Paul J Novotny
Daniel V Satele
Breanna M Linquist
Sherry Wolf
Debra L Barton

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Survivorship research established investigator awardK05CA124477 · NCI · MAYO CLINIC ROCHESTER · PI LOPRINZI, CHARLES L · 2008 to 2012
$777k
Ambulatory Sternal Skin Conductance Recording ToolR43EB006013 · NIBIB · ADVANCED MEDICAL ELECTRONICS CORPORATION · PI HAVEY, GARY D · 2005 to 2005
$250k
Self-Reported Menopausal Symptomatology and Wireless Skin Conductance RecorderR43AT004075 · NCCIH · ADVANCED MEDICAL ELECTRONICS CORPORATION · PI HAVEY, GARY D · 2006 to 2006
$244k
NCATS NIH HHS UL1 TR000135NCCIH NIH HHS R43 AT004075NCI NIH HHS CA 124477NCI NIH HHS K05 CA124477NCI NIH HHS P30 CA015083NIBIB NIH HHS R43 EB006013NIBIB NIH HHS R43 EB 06013
6 · The paper itself

Abstract

objectiveThis study aims to examine the accuracy of a new sternal skin conductance (SSC) device in measuring hot flashes and to assess the acceptability of the device by women.

methodsThree small descriptive pilot studies were performed using two sequential prototypes of the SSC device developed by an engineering device company in the Midwest. The devices were worn either in a monitored setting for 24 hours or in an ambulatory setting for 5 weeks. During the study period, women recorded hot flashes in a prospective hot flash diary and answered questions about the acceptability of wearing the SSC device.

resultsThe first prototype was not able to collect any analyzable skin conductance data owing to various malfunction issues, including poor conductance and battery failure. However, 16 women wore the device for 5 weeks and reported that wearing the device was acceptable, although 31% stated that it interfered with daily activities. Hot flash data from the second prototype revealed a 24% concordance rate between self-reported and device-recorded hot flashes.

conclusionsFindings from these studies support discordance between device-recorded and self-reported hot flashes. In addition, the studies reveal further limitations of SSC monitoring, including difficulties with data collection and lack of consistency in interpretation. Based on these results and other recent trials identifying issues with SSC methodology, it is time to find a better physiologic surrogate measure for hot flashes.

Indexed as

MenopauseSternumFemaleGalvanic Skin ResponseHistory, AncientHot FlashesHumansMiddle AgedMonitoring, AmbulatoryMonitoring, PhysiologicPilot ProjectsProspective StudiesSelf ReportSkinSkin TemperatureWomen's Health

Identifiers

PMID23571528
PMCPMC3724754

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.