Evidence map›Paper›PMID 23571210›Full record

ReviewDevelopment (Cambridge, England)2013

Molecular pathways regulating mitotic spindle orientation in animal cells.

Michelle S Lu, Christopher A Johnston

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 172 citations in OpenAlex.

  1. Review
  2. Article
  3. Marine Model Organisms for Mechanobiology Studies.Results and problems in cell differentiation · 2026
    Review
  4. Article
  5. Article
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  12. Frontiers in cell and developmental biology · 2023
    Article
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  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michelle S LuInstitute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA.
Christopher A Johnston
University of New Mexico · USUniversity of Oregon · US

Funding

Intramural NIH HHS
6 · The paper itself

Abstract

Orientation of the cell division axis is essential for the correct development and maintenance of tissue morphology, both for symmetric cell divisions and for the asymmetric distribution of fate determinants during, for example, stem cell divisions. Oriented cell division depends on the positioning of the mitotic spindle relative to an axis of polarity. Recent studies have illuminated an expanding list of spindle orientation regulators, and a molecular model for how cells couple cortical polarity with spindle positioning has begun to emerge. Here, we review both the well-established spindle orientation pathways and recently identified regulators, focusing on how communication between the cell cortex and the spindle is achieved, to provide a contemporary view of how positioning of the mitotic spindle occurs.

Indexed as

Cell PolarityMitosisAnimalsAsymmetric Cell DivisionCell Cycle ProteinsCell DifferentiationCell ShapeDrosophilaMicrotubulesPhosphorylationProtein Interaction MappingSignal TransductionSpindle ApparatusCell Cycle Proteins

Identifiers

PMID23571210
PMCPMC3631962
OpenAlexW2116352427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.