Evidence map›Paper›PMID 23569993›Full record

ArticleAsian Pacific journal of tropical biomedicine2012

Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn.

Apurba Sarker Apu, Mahmuda Sultana Liza, A T M Jamaluddin, Md Amran Howlader, Repon Kumer Saha, Farhana Rizwan, Nishat Nasrin

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Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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  3. Article
  4. The Current Landscape of Bioactive Molecules against DENV: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2023
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  10. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Apurba Sarker ApuDepartment of Pharmacy, East West University, Dhaka-1212, Bangladesh.
Mahmuda Sultana Liza
A T M Jamaluddin
Md Amran Howlader
Repon Kumer Saha
Farhana Rizwan
Nishat Nasrin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the bioactivities of crude n-hexane, ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn. (B. diffusa) and its phytochemical analysis.

methodsThe identification of phytoconstituents and assay of antioxidant, thrombolytic, cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.

resultsThe results showed that the plant extracts were a rich source of phytoconstituents. Methanol extract showed higher antioxidant, thrombolytic activity and less cytotoxic activity than those of n-hexane and ethyl acetate extracts of B. diffusa. Among the bioactivities, antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of natural antioxidant. In case of antimicrobial screening, crude extracts of the plant showed remarkable antibacterial activity against tested microorganisms. All the extracts showed significant inhibitory activity against Candida albicuns, at a concentration of 1000 µg/disc.

conclusionsThe present findings suggest that, the plant widely available in Bangladesh, could be a prominent source of medicinally important natural compounds.

Indexed as

AnimalsAnti-Infective AgentsAntioxidantsArtemiaBacteriaBiphenyl CompoundsLethal Dose 50Microbial Sensitivity TestsNitric OxideNyctaginaceaePhenolsPhytochemicalsPicratesPlant Components, AerialPlant Extracts1,1-diphenyl-2-picrylhydrazylAnti-Infective AgentsAntioxidantsBiphenyl CompoundsNitric OxidePhenolsPhytochemicalsPicratesPlant ExtractsAntimicrobialAntioxidantBoerhavia diffusaCytotoxicDPPHNOThrombolytic

Identifiers

PMID23569993
PMCPMC3609381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.