Evidence map›Paper›PMID 23569981›Full record

ArticleAsian Pacific journal of tropical biomedicine2012

In vitro scolicidal effect of Satureja khuzistanica (Jamzad) essential oil.

Mohammad Moazeni, Mohammad Jamal Saharkhiz, Ali Akbar Hoseini, Amir Mootabi Alavi

Open access · bronzeAbstract read
In one paragraph

Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Essential Oils as Novel Anthelmintic Drug Candidates.Molecules (Basel, Switzerland) · 2022
    Review
  4. A systematic appraisal of the use of carvacrol-rich plants to treat hydatid cysts.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Annals of medicine and surgery (2012) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mohammad MoazeniDepartment of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, 71345-1731, Iran.
Mohammad Jamal Saharkhiz
Ali Akbar Hoseini
Amir Mootabi Alavi
Shiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the scolicidal effect of the Satureja khuzistanica (S. khuzistanica)essential oil from aerial parts of this herbal plant.

methodsThe essential oil was obtained by hydrodistillation method. Gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) were employed to determine the chemical composition of the essential oil. Protoscolices were collected aseptically from sheep livers containing hydatid cyst. Protoscolices were exposed to various concentrations of the oil (3, 5 and 10 mg/mL) for 10, 20, 30, and 60 min. Viability of protoscolices was confirmed by 0.1% eosin staining.

results: A total of 19 compounds representing 97.6% of the total oil, were identified. Carvacrol (94.9%) was found to be the major essential oil constituent. Scolicidal activity of S. khuzistanica essential oil at concentration of 3 mg/mL was 28.58, 32.71, 37.20 and 42.02%, respectively. This essential oil at concentration of 5 mg/mL killed 51.33, 66.68, 81.12, and 100% of protoscolices after 10, 20, 30 and 60 min, respectively. One hundred scolicidal effect was observed with S. khuzistanica essential oil at the concentration of 10 mg/mL after 10 min (comparing with 7.19% for control group).

conclusionsThe essential oil of S. khuzistanica is rich in carvacrol and may be used as a natural scolicidal agent.

Indexed as

AnimalsAnthelminticsBiological AssayEchinococcusGas Chromatography-Mass SpectrometryMicroscopyOils, VolatileSaturejaSheepSurvival AnalysisAnthelminticsOils, VolatileCarvacrolEssential oilHydatid cystSatureja khuzistanicaScolicidal

Identifiers

PMID23569981
PMCPMC3609354
OpenAlexW2068012967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.