ArticleAsian Pacific journal of tropical biomedicine2012
Molecular study of HCV detection, genotypes and their routes of transmission in North West Frontier Province, Pakistan.
Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Hepatitis C virus prevalence and genotype distribution in Pakistan: Comprehensive review of recent data.World journal of gastroenterology · 2016Pooled it
- Epidemiology, risk factors, and pathogenesis associated with a superbug: A comprehensive literature review on hepatitis C virus infection.SAGE open medicine · 2022Review
- Detection, quantification and genotype distribution of HCV patients in Lahore, Pakistan by real-time PCR.African health sciences · 2020Article
- Prevalence of hepatitis-C virus genotypes and potential transmission risks in Malakand Khyber Pakhtunkhwa, Pakistan.Virology journal · 2017Article
- Global epidemiology and burden of HCV infection and HCV-related disease.Nature reviews. Gastroenterology & hepatology · 2017Review
- Prevalence of Hepatitis C Virus Genotypes Among Patients in Countries of the Eastern Mediterranean Regional Office of WHO (EMRO): A Systematic Review and Meta-Analysis.Hepatitis monthly · 2016Review
- Diagnostically untypable hepatitis C virus variants: it is time to resolve the problem.World journal of gastroenterology · 2014Article
- Prevalence of hepatitis C virus genotypes in district bannu, khyber pakhtunkhwa, pakistan.Hepatitis research and treatment · 2014Article
- Prevalence of HCV genotypes in district Mardan.Virology journal · 2013Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine hepatitis C virus (HCV) genotypes and explore the associated risk factors in chronic HCV patients.
methodsA total of 116 patients with chronic hepatitis C were subjected to polymerase chain reaction (PCR) based detection out of which 112 chronic HCV patients [53 male (47.32%), 59 female (52.68%); mean age (43.76±16.40) years; mean BMI (23.8±3.9) kg] were enrolled in this study. The frequency of 6 HCV genotypes and associated risk factors were evaluated from five districts of North West Frontier Province (NWFP).
resultsGenotype 3 was the most prevalent in 73 samples (65.17%) followed by genotype 1 in 24 (21.42%) and genotype 2 in 13 (11.60%) samples. Genotype 3 had significantly high prevalence (P=0.000 2). The results showed that 48 (42.85%) samples were infected with HCV 3a; 25 (22.32%) with 3b; 14 (12.50%) with 1a; 10 (8.92%) with 1b; 11 (9.82%) with 2a; 2 (1.78%) with 2b; and 2 were untypable. The distribution of HCV genotypes in Mardan, Charsadda, Peshawar, Sawabi and Nowshehra districts was different. Use of unsterile equipment for medication, barbers and previous history of hospitalization were the main risk factors for HCV transmission.
conclusionsGenotype 3a and 3b, 1a, 1b and 2a are the common genotypes in NWFP. Genotype 4, 5, and 6 can not be found in a single sample. The level of awareness about various modes of transmission of HCV among the population is found to be very low.
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