ArticleAsian Pacific journal of tropical biomedicine2012
Antidiabetic activities of ethanolic extract and fraction of Anthocleista djalonensis.
Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 29 citations in OpenAlex.
- Potential antidiabetic phytochemicals in plant roots: a review of in vivo studies.Journal of diabetes and metabolic disorders · 2021Review
- Article
- Antidiabetic and antihyperlipidemic effect ofSaudi journal of biological sciences · 2020Article
- Experimental Validation of Antidiabetic Potential ofIndian journal of clinical biochemistry : IJCB · 2017Article
- Saponin as regulator of biofuel: implication for ethnobotanical management of diabetes.Journal of physiology and biochemistry · 2014Review
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
objectiveTo evaluate the antidiabetic activities of ethanolic root extract/fraction of Anthocleista djalonensis (A. djalonensis) in alloxan-induced diabetic rats.
methodsA. djalonensis root extract/fractions (37-111 mg/kg) were administered to alloxan-induced diabetic rats for 14 days and blood glucose levels (BGLs) of the diabetic rats were monitored at intervals of hours and days throughout the duration of the treatment.
resultsTreatment of alloxan-induced diabetic rats with the extract/fractions caused a significant (P<0.001) reduction in fasting BGLs of the diabetic rats both in acute study and prolonged treatment (2 weeks). The activities of the extract and fractions were more than that of the reference drug, glibenclamide.
conclusionsThese results suggest that the root extract/fractions of A. djalonensis possess antidiabetic effect on alloxan-induced diabetic rats and this justifies its use in ethnomedicine and can be exploited in the management of diabetes.
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