ArticleAsian Pacific journal of tropical biomedicine2012
Evaluation of safety profile of black shilajit after 91 days repeated administration in rats.
Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation.Journal of medicinal food · 2016Trial
- Biogeochemical Evaluation of Shilajit: Testosterone-Modulating Effects, In Vivo Toxicity and Lipid Profile Analysis.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Article
- The physiological effects of administering different concentrations of Shilajit to Awassi lambs and their impact on productive trait and blood parameters and some biochemical measurements.Open veterinary journal · 2026Article
- Humic Acid Derived from Agricultural Biomass Mitigates Alveolar Bone Loss and Modulates Systemic Inflammatory Cytokines in Rats with Periodontitis.Current topics in medicinal chemistry · 2025Article
- Hazardous or Advantageous: Uncovering the Roles of Heavy Metals and Humic Substances in Shilajit (Phyto-mineral) with Emphasis on Heavy Metals Toxicity and Their Detoxification Mechanisms.Biological trace element research · 2024Review
- Therapeutic Efficiency of Humic Acids in Intoxications.Life (Basel, Switzerland) · 2023Review
- Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment.Scientific reports · 2021Article
- The effect of humic acid in chronic deoxynivalenol intoxication.Environmental science and pollution research international · 2021Article
- Lead and cadmium assessment in 54 Indian herbal medicines: traditional and marketed varieties-a questionable allegation!!Environmental science and pollution research international · 2020Article
- Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals.Ancient science of lifeArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the safety of shilajit by 91 days repeated administration in different dose levels in rats.
methodsIn this study the albino rats were divided into four groups. Group I received vehicle and group II, III and IV received 500, 2 500 and 5 000 mg/kg of shilajit, respectively. Finally animals were sacrificed and subjected to histopathology and iron was estimated by flame atomic absorption spectroscopy and graphite furnace.
resultsThe result showed that there were no significant changes in iron level of treated groups when compared with control except liver (5 000 mg/kg) and histological slides of all organs revealed normal except negligible changes in liver and intestine with the highest dose of shilajit. The weight of all organs was normal when compared with control.
conclusionsThe result suggests that black shilajit, an Ayurvedic formulation, is safe for long term use as a dietary supplement for a number of disorders like iron deficiency anaemia.
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