Evidence map›Paper›PMID 23569870›Full record

ArticleAsian Pacific journal of tropical biomedicine2012

Effect of quercetin against lindane induced alterations in the serum and hepatic tissue lipids in wistar rats.

Viswanadha Vijaya Padma, Gurusamy Lalitha, Nicholson Puthanveedu Shirony, Rathinasamy Baskaran

Open access · bronzeAbstract read
In one paragraph

Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Bioinformatics and biology insights · 2024
    Article
  5. Bioactive Substances and Biological Functions inMolecules (Basel, Switzerland) · 2023
    Review
  6. Research progress of quercetin in cardiovascular disease.Frontiers in cardiovascular medicine · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Viswanadha Vijaya PadmaAnimal tissue culture and Molecular genetics Laboratory, Department of Biotechnology, School of Biotechnology and Genetic Engineering, Bharathiar University, Coimbatore-641 046, Tamilnadu, India.
Gurusamy Lalitha
Nicholson Puthanveedu Shirony
Rathinasamy Baskaran
Bharathiar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effect of quercetin (flavonoid) against lindane induced alterations in lipid profile of wistar rats.

methodsRats were administered orally with lindane (100 mg/kg body weight) and quercetin (10 mg/kg body weight) for 30 days. After the end of treatment period lipid profile was estimated in serum and tissue.

resultsElevated levels of serum cholesterol, triglycerides, low density lipoprotein (LDL), very Low Density Lipoprotein (VLDL) and tissue triglycerides, cholesterol with concomitant decrease in serum HDL and tissue phospholipids were decreased in lindane treated rats were found to be significantly decreased in the quercetin and lindane co-treated rats.

conclusionsOur study suggests that quercetin has hypolipidemic effect and offers protection against lindane induced toxicity in liver by restoring the altered levels of lipids. The quercetin cotreatment along with lindane for 30 days reversed these biochemical alterations in lipids induced by lindane.

Indexed as

AnimalsFemaleHexachlorocyclohexaneLipid MetabolismLipidsLiverOxidative StressQuercetinRatsRats, WistarHexachlorocyclohexaneLipidsQuercetinHigh density lipoproteinLindaneLow density lipoproteinOxidative stressQuercetinTriglyceridesVery low density lipoprotein

Identifiers

PMID23569870
PMCPMC3609243
OpenAlexW2101858583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.