ArticleAsian Pacific journal of tropical biomedicine2012
Effects of Mirazid(®) and myrrh volatile oil on adult Fasciola gigantica under laboratory conditions.
Article in Asian Pacific journal of tropical biomedicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- The Effect of Sitz Bath of Hydro-Alcoholic Extract of Myrrh Gum on Episiotomy Wound Healing in Nulliparous Women.Journal of family & reproductive health · 2019Article
- Comparison of the Antibacterial Efficacy ofEvidence-based complementary and alternative medicine : eCAM · 2019Article
- Molecular characterization ofSaudi journal of biological sciences · 2019Article
- Epidemiology and economic loss of fasciolosis and dicrocoeliosis in Arak, Iran.Veterinary world · 2018Article
- Larvicidal activity of camphor and lavender oils against sheep blowfly,Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- A retrospective survey of liver flukes in livestock based on abattoir data in Kermanshah, west of Iran.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Tegumental histological effects of Mirazid(®) and myrrh volatile oil on adult Fasciola gigantica.Asian Pacific journal of tropical biomedicine · 2013Article
- Anthelmintics Resistance; How to Overcome it?Iranian journal of parasitology · 2013Article
- HPLC characterization of molluscicidal component of Tamarindus indica and its mode of action on nervous tissue of Lymnaea acuminata.Journal of Ayurveda and integrative medicineArticle
- Antiparasitic Activity of Mirazid, Myrrh Total Oil and Nitazoxanide Compared to Praziquantel onIranian journal of parasitologyArticle
- Tegumental Effects of Methanolic Extract ofIranian journal of parasitologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effects of Mirazid(®) and myrrh volatile oil on adult Fasciola gigantica (F. gigantica ) under laboratory conditions.
methodsThe effects of oleoresin extract of myrrh (Mirazid(®)) and myrrh volatile oil on the surface morphology of adult F. gigantica following treatment in vitro had been determined by scanning electron microscopy. The results were compared with those observed in the fluke tegument following incubation in triclabendazole sulphoxide (TCBZ-SO), active form, (Fasinex(®), Ciba-Geigy).
resultsObservations of the efficacy of Mirazid(®) oleoresin extract and myrrh volatile oil indicated that both products showed dose-dependent anthelmintic efficacy. The anterior half of the fluke was consistently more severely affected than the posterior half. The surface changes induced by Mirazid(®) oleoresin extract were less severe than those observed after exposure to either myrrh volatile oil or TCBZ-SO. Flukes showed swelling after these treatments, but its level and blebbing were much greater with myrrh volatile oil; in which patches of tegumental sloughing were observed in the apical cone and the posterior mid-body region of flukes. This was not observed after treatment with Mirazid(®) oleoresin extract.
conclusionsThe comparatively more disruption, observed in myrrh volatile oil exposed specimens, compared to that exposed to Mirazid(®) oleoresin extract might suggest that the anthelmintic activity of Mirazid(®) oleo resin extract was attributed to its content of volatile oil. So, increasing the concentration of myrrh volatile oil in Mirazid(®) might possibly help to developing its anthelmintic activity.
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