ArticleAsian Pacific journal of tropical biomedicine2011
Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume.
Article in Asian Pacific journal of tropical biomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 38 citations in OpenAlex.
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- A comparative study of the antioxidant, antimicrobial, cytotoxic and thrombolytic potential of the fruits and leaves of Spondias dulcis.Asian Pacific journal of tropical biomedicine · 2013Article
- Evaluation of anti-bacterial and anti-oxidant potential of andrographolide and echiodinin isolated from callus culture of Andrographis paniculata Nees.Asian Pacific journal of tropical biomedicine · 2013Article
- In vitro antioxidant activities of Solanum surattense leaf extract.Asian Pacific journal of tropical biomedicine · 2013Article
- Pharmacognosy of Enicostemma littorale: a review.Asian Pacific journal of tropical biomedicine · 2013Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicostemma littorale (E. littorale) Blume (Ens) against ethanol induced hepatic injury in albino rats.
methodsMale albino rats of six numbers in each group were undertaken for study. Hypolipidaemic and antioxidant effect of E. littorale Blume (Ens) aqueous leaf extract at a dosage of 250 mg/kg bw was evaluated.
resultsLevels of serum and tissue cholesterol, triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide were increased in ethanol treated rats. The activity levels of liver antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and glutathione-s-transferase (GST) were decreased. After adiminstration of extract of E. littorale Blume, levels of cholesterol, triglycerides and free fatty acids were decreased in serum and liver tissue, levels of TBARS and lipid hydroperoxide were decreased, and liver antioxidant enzymes were increased in liver tissue.
conclusionsIt can be concluded that the aqueous leaf extract of E. littorale Blume (Ens) has potent restorative effect on hyperlipidaemic and oxidative stress.
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Registered trials
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