ArticleJournal of anesthesia1994
RETRACTED ARTICLE: Airway occlusion pressure is an indicator of respiratory depression with isoflurane.
Article in Journal of anesthesia, 1994. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Retraction · 2013-03-01Falsification/Fabrication of Data · Investigation by Company/Institution · Investigation by Third Party · Misconduct - Official Investigation(s) and/or Finding(s) · Misconduct by Author ·
- Retracted
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to elucidate the respiratory depressant effects of isoflurane (0%-1.0%) using airway occlusion pressure (P0.1), a known index of the output of the respiratory centers, in ten anesthetized patients. P0.1 was measured as the pressure change obtained after the first 0.1 sec of spontaneous inspiration against the occluded airway. A significant decrease in minute volume ([Formula: see text]) and a significant increase in PaCO 2 were not observed during the periods of isoflurane 1.0% at the end-tidal concentration compared with those of control period (0% isoflurane) (P<0.05), whereas a significant decrease in P0.1 was observed during the period of isoflurane 0.5%. Our results suggested that P0.1 was a more sensitive indicator of respiratory depression than PaCO 2 or[Formula: see text], and the respiratory center was depressed with a considerably lower concentration (0.5%) of isoflurane.
Identifiers
23568106What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.