Evidence map›Paper›PMID 23568039›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2014

Intranasal trigeminal sensitivity: measurements before and after nasal surgery.

M Scheibe, S Schulze, C A Mueller, B Schuster, Thomas Hummel

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06020937 (Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06020937 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis

Typeobservational_patient_registrySponsorUniversity of CataniaRan2026 to 2028Enrolled200ConditionsMultiple SclerosisArmsTDI, Trigeminal Test, Cognitive Evaluation by Montreal Cognitive Assessment, Anxiety and Depression questionnaire, Visual Analogue Scale Ratings
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Implications of Intranasal Trigeminal Nerve Function on the Surgical Management of Nasal Obstruction.ORL; journal for oto-rhino-laryngology and its related specialties · 2025
    Review
  3. Intranasal trigeminal sensitivity to mechanical stimuli is associated with the perception of nasal patency.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  4. Olfactory Function and Olfactory Disorders.Laryngo- rhino- otologie · 2023
    Article
  5. [Correlation between nasal mucosal temperature change and nasal airflow perception].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Review
  6. Article
  7. Effects of "trigeminal training" on trigeminal sensitivity and self-rated nasal patency.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M ScheibeDepartment of Otorhinolaryngology, Smell and Taste Clinic, University of Dresden Medical School, Fetscherstr. 74, 01307, Dresden, Germany.
S Schulze
C A Mueller
B Schuster
Thomas Hummel
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasal surgeries constitute an extensive manipulation of the nasal mucosa and therefore of structures related to trigeminal and olfactory sensitivity. While olfactory changes due to nasal surgery are relatively well investigated, there are only very few studies regarding trigeminal sensitivity. Aim of the present study was to investigate sensory changes after nasal surgery with special regard to the trigeminal sensitivity. In 38 patients prior to and around 12 weeks after nasal surgery the following psychophysical measures were performed: odor identification, odor discrimination, phenyl ethyl alcohol odor threshold, sensitivity to trigeminal stimuli, trigeminal detection thresholds and trigeminal pain thresholds. These results were compared to those of a control group (43 healthy volunteers). Psychophysical olfactory and trigeminal testing showed no major changes in patients after surgery compared to the control group. Independent from the time of measurement higher trigeminal detection thresholds were found in patients compared to healthy subjects, meaning that trigeminal thresholds were already increased before surgery. The present study revealed a decreased trigeminal sensitivity in patients already before surgery. It may be hypothesized that patients also exhibit a decreased sensitivity for nasal airflow, which may also contribute to the patients' impression of impaired nasal breathing.

Indexed as

AdultFemaleHumansMaleMiddle AgedNasal MucosaNose Deformities, AcquiredOdorantsOlfaction DisordersPostoperative PeriodPreoperative PeriodRhinoplastySensory ThresholdsTrigeminal NerveYoung Adult

Identifiers

PMID23568039
OpenAlexW1996507925

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.