Evidence map›Paper›PMID 23568027›Full record

ArticleJournal of the American Society for Mass Spectrometry2013

Absorption-mode Fourier transform mass spectrometry: the effects of apodization and phasing on modified protein spectra.

Yulin Qi, Huilin Li, Rebecca H Wills, Pilar Perez-Hurtado, Xiang Yu, David P A Kilgour, Mark P Barrow, Cheng Lin, Peter B O'Connor

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Fellgett Revisited: On the Nature of Noise in Two-Dimensional Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Phase relationships in two-dimensional mass spectrometry.Journal of the American Society for Mass Spectrometry · 2019
    Article
  7. Article
  8. Autopiquer - a Robust and Reliable Peak Detection Algorithm for Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2017
    Article
  9. Article
  10. Article
  11. Mass spectral peak distortion due to Fourier transform signal processing.Journal of the American Society for Mass Spectrometry · 2014
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yulin QiDepartment of Chemistry, University of Warwick, Coventry, UK.
Huilin Li
Rebecca H Wills
Pilar Perez-Hurtado
Xiang Yu
David P A Kilgour
Mark P Barrow
Cheng Lin
Peter B O'Connor

Funding

XI INTERNATIONAL SYMPOSIUM ON AMYLOIDOSISP41RR010888 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 1996 to 2011
$18.6M
Mass Spectrometry Resource for Biology and MedicineP41GM104603 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COSTELLO, CATHERINE E. · 2012 to 2017
$10.4M
Defining the IsoAspartomeR01GM078293 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LIN, CHENG · 2007 to 2011
$1.5M
NCRR NIH HHS P41 RR010888NIGMS NIH HHS P41 GM104603NIGMS NIH HHS R01 GM078293
6 · The paper itself

Abstract

The method of phasing broadband Fourier transform ion cyclotron resonance (FT-ICR) spectra allows plotting the spectra in the absorption-mode; this new approach significantly improves the quality of the data at no extra cost. Herein, an internal calibration method for calculating the phase function has been developed and successfully applied to the top-down spectra of modified proteins, where the peak intensities vary by 100×. The result shows that the use of absorption-mode spectra allows more peaks to be discerned within the recorded data, and this can reveal much greater information about the protein and modifications under investigation. In addition, noise and harmonic peaks can be assigned immediately in the absorption-mode.

Indexed as

Fourier AnalysisAbsorptionAcousticsArtifactsMass SpectrometryPeptidesProteinsSignal-To-Noise RatioPeptidesProteins

Identifiers

PMID23568027
PMCPMC4024093

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.