ArticleJournal of diabetes science and technology2013
Analysis: on the path to overcoming glucose-sensor-induced foreign body reactions.
Article in Journal of diabetes science and technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Injury to tissue caused by device penetration of the skin triggers formation of extracellular traps.Communications biology · 2025Article
- The Challenges of Postoperative Tissue Flap Vitality Monitoring in Obese Individuals.Journal of clinical medicine · 2025Review
- Analytical Performance of the Factory-Calibrated Flash Glucose Monitoring System FreeStyle Libre2Sensors (Basel, Switzerland) · 2023Article
- Glucose Sensing in the Subcutaneous Tissue: Attempting to Correlate the Immune Response with Continuous Glucose Monitoring Accuracy.Diabetes technology & therapeutics · 2018Article
- Modeling the Physiological Factors Affecting Glucose Sensor Function in Vivo.Journal of diabetes science and technology · 2015Article
- Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals.PloS one · 2015Article
- Macrophage embedded fibrin gels: an in vitro platform for assessing inflammation effects on implantable glucose sensors.Biomaterials · 2014Article
- Continuous glucose monitoring in the subcutaneous tissue over a 14-day sensor wear period.Journal of diabetes science and technology · 2013Article
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1 author at 1 institution in 1 country.
Funding
Abstract
It is generally accepted that unreliable in vivo performance of implantable glucose sensors originates, in large part, from tissue reactions to the implanted sensor, including foreign body reactions (i.e., inflammation, fibrosis, and vessel regression). Development of glucose sensor coatings with increased biocompatibility would contribute to the development of a reliable long-term glucose sensor. In this issue of Journal of Diabetes Science and Technology, Van den Bosch and coauthors report on their initial in vitro results on a candidate biocompatibility coating for sensors (silica nanoparticle- polyethylene-glycol-based coating). Although the initial standard testing is encouraging, it is important that sensor-specific testing protocol be utilized to more accurately predict sensor performance in vivo. The development and application of sensor-specific testing standards will likely speed the development of biocompatible coatings that will increase sensor accuracy and lifespan in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.