Evidence map›Paper›PMID 23566496›Full record

ArticleSchizophrenia research2013

RETRACTED: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients.

Jagadeesh Sridhara Rao, Hyung-Wook Kim, Gaylia Jean Harry, Stanley Isaac Rapoport, Edmund Arthur Reese

RetractedOpen access · greenAbstract readRetracted Publication
In one paragraph

Article in Schizophrenia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 51 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 5 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 5 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Kynurenine is correlated with IL-1β in plasma of schizophrenia patients.Journal of neural transmission (Vienna, Austria : 1996) · 2018
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

  • Retraction · 2017-07-04Falsification/Fabrication of Data · Investigation by Company/Institution · Investigation by Journal/Publisher · Investigation by ORI · Misconduct - Official Investigation(s) and/or Finding(s) · Misconduct by Author ·
  • Retracted
5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Jagadeesh Sridhara RaoBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA. Electronic address: jrao@mail.nih.gov.
Hyung-Wook KimBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Gaylia Jean HarryLaboratory of Toxicology and Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Stanley Isaac RapoportBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Edmund Arthur ReeseBrain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Institute on Aging · USNational Institute of Environmental Health Sciences · USNational Institute on Aging · USNational Institutes of Health · US

Funding

Environmentally Induced Alterations In Neuron And Glia Development and AgingZIAES021164 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI HARRY, GAYLIA JEAN · 2009 to 2021
$15.4M
A Natonal Resource for Postmortem Brain ResearchR24MH068855 · NIMH · MC LEAN HOSPITAL (BELMONT, MA) · PI BENES, FRANCINE M. · 2003 to 2012
$14.8M
Lipids in Human Brain DiseaseZIAAG000428 · NIA · NATIONAL INSTITUTE ON AGING · PI RAPOPORT, STANLEY I. · 2009 to 2016
$2.6M
Intramural NIH HHS Z99 AG999999NIA NIH HHS R99 AG999999NIMH NIH HHS R24 MH068855
6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editors. The National Institutes of Health has found that Dr. Jagadeesh S. Rao engaged in research misconduct by falsifying data. Data in Figures 1A, 1E, 3E and 3F were falsified. Dr. Rao was solely responsible for the falsification. None of the other authors are implicated in any way.

Indexed as

AdultAgedAnalysis of VarianceArachidonic AcidCytokinesFemaleFrontal LobeGene Expression RegulationHLA-DR AntigensHumansMaleMicrogliaMiddle AgedNerve Tissue ProteinsNitric Oxide Synthase Type IIPostmortem ChangesArachidonic AcidCytokinesHLA-DR AntigensNerve Tissue ProteinsNitric Oxide Synthase Type IIProto-Oncogene Proteins c-fosReceptors, N-Methyl-D-AspartateRNA, Messenger

Identifiers

PMID23566496
PMCPMC3812915
OpenAlexW2082034244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.