Evidence map›Paper›PMID 23565928›Full record

ArticleAIDS patient care and STDs2013

From efficacy to effectiveness: facilitators and barriers to PrEP acceptability and motivations for adherence among MSM and transgender women in New York City.

Sarit A Golub, Kristi E Gamarel, H Jonathon Rendina, Anthony Surace, Corina L Lelutiu-Weinberger

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS patient care and STDs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04048382 (Developing a Patient Navigation Intervention for PrEP Continuum of Care Among Young Latino MSM), which is not on this map. Cited by 244 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
244citing papers in PubMed, 6 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04048382 nacompletednot on this mapstarted 2019, after this paper: background citation

Developing a Patient Navigation Intervention for PrEP Continuum of Care Among Young Latino MSM (PrEParate)

TypeinterventionalSponsorSan Diego State UniversityRan2019 to 2021Enrolled57ConditionsHIV/AIDSArmsPatient Navigation, Usual Care
3 · Its place in the literature

Who cites it

244 citing papers in PubMed, 6 syntheses or guidelines pooled it, 355 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Validation of the PrEP Use Self-Efficacy (PrEP-Use) Scale Among Sexual Minority Men.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
    Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
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  15. Metabolic Effects of Preexposure Prophylaxis With Coformulated Tenofovir Disoproxil Fumarate and Emtricitabine.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Trial
  16. Trial
  17. Review
  18. Article
  19. Article
  20. Article

184 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sarit A GolubDepartment of Psychology, Hunter College of the City University of New York, New York, New York 10065, USA. sarit.golub@hunter.cuny.edu
Kristi E Gamarel
H Jonathon Rendina
Anthony Surace
Corina L Lelutiu-Weinberger
Hunter College · USThe Graduate Center, CUNY · USCity University of New York · US

Funding

Impact of PrEP Messaging on Comprehension, Acceptability, and Risk Among MSMR01MH095565 · NIMH · HUNTER COLLEGE · PI GOLUB, SARIT A · 2011 to 2013
$1.5M
Interpersonal and intrapersonal conflict and their association with substance useF31MH095622 · NIMH · CUNY GRADUATE SCH AND UNIV CTR · PI RENDINA, H. JONATHON · 2012 to 2014
$69k
NIMH NIH HHS F31 MH095622NIMH NIH HHS R01 MH095565NIMH NIH HHS R01MH095565
6 · The paper itself

Abstract

This study examined potential facilitators and barriers to pre-exposure prophylaxis (PrEP) use and their association with PrEP acceptability and motivations for adherence among 184 MSM and transgender women living in New York City. Participants were presented with educational information about PrEP and completed a computerized survey. Overall, 55.4% of participants reported willingness to take PrEP. The most highly endorsed barriers to PrEP use were health concerns, including both long-term impacts and short-term side effects, questions about PrEP's impact on future drug resistance, and concerns that PrEP does not provide complete protection against HIV. The most highly endorsed facilitator was free access to PrEP, followed by access to support services such as regular HIV testing, sexual health care/monitoring, and access to one-on-one counseling. Participants of color rated both barriers and facilitators as more important than their White counterparts. In multivariate models, barrier and facilitator scores significantly predicted not only PrEP acceptability, but also motivation for PrEP adherence among those who were likely to use PrEP. PrEP implementation programs should consider addressing these barriers and facilitators in protocol and policy development. Findings underscore the importance of support services, such as sexual health counseling, to the success of PrEP as a prevention strategy.

Indexed as

Medication AdherenceMotivationAdolescentAdultAnti-HIV AgentsCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedNew York CityPatient Acceptance of Health CareAnti-HIV Agents

Identifiers

PMID23565928
PMCPMC3624632
OpenAlexW2062531750

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.