ArticleThe journal of headache and pain2013
Peripheral endothelial function and arterial stiffness in patients with chronic migraine: a case-control study.
Article in The journal of headache and pain, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 65 citations in OpenAlex.
- D-dimer in Marfan syndrome: effect of obstructive sleep apnea induced blood pressure surges.American journal of physiology. Heart and circulatory physiology · 2022Trial
- Phasic perfusion dynamics among migraine subtypes: a multimodel arterial spin labeling investigation.The journal of headache and pain · 2024Article
- Lipids, lipid-modifying drug target genes and migraine: a Mendelian randomization study.The journal of headache and pain · 2023Article
- Molecular mechanisms of hormones implicated in migraine and the translational implication for transgender patients.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- The Role of Endothelial Dysfunction in the Pathophysiology and Cerebrovascular Effects of Migraine: A Narrative Review.Journal of clinical neurology (Seoul, Korea) · 2021Review
- Perivascular neurotransmitters: Regulation of cerebral blood flow and role in primary headaches.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Review
- Lack of association between urotensin-II (UTS2) gene polymorphisms (Thr21Met and Ser89Asn) and migraine.Bosnian journal of basic medical sciences · 2017Article
- High asymmetric dimethylarginine, symmetric dimethylarginine and L-arginine levels in migraine patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017Article
- Superior Effects of High-Intensity Interval Training vs. Moderate Continuous Training on Arterial Stiffness in Episodic Migraine: A Randomized Controlled Trial.Frontiers in physiology · 2017Article
- Higher augmentation index is associated with tension-type headache and migraine in middle-aged/older humans with obesity.Obesity (Silver Spring, Md.) · 2016Article
- The count of tender rather than swollen joints correlates with aortic stiffness in patients with rheumatoid arthritis.SpringerPlus · 2016Article
- Endothelial dysfunction state in migraine headache and neutrally mediated syncope in children and young adults.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Article
- Peripheral vascular dysfunction in migraine: a review.The journal of headache and pain · 2013Review
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMigraine is a complex and disabilitating neurovascular disorder predominantly affecting women. There is strong evidence that nitric oxide is critically involved in migraine pathophysiology. The aim of the present study was to test the hypothesis that chronic migraine is associated with ultrasonographic endothelial dysfunction and increase in arterial stiffness. These parameters were assessed using a novel plethysmograph by peripheral arterial tonometry.
methodsTwenty-one patients with chronic migraine and twenty-one healthy controls matched by sex and gender were recruited. Measurement of the ultrasonographic endothelial function and augmentation index were made according to manufacturer's protocol.
resultsThe mean of patient's peripheral arterial tonometry ratios was 1.93 ± 0.39 and for healthy control 2.21 ± 0.44 (p=0.040). The median of patients' augmentation index was -6,0 (IQR: 6.5 to -15) in healthy controls and 9.0 (IQR: 4 to 12) in chronic migraine, (p=0.002).
conclusionsPatients with chronic migraine have ultrasonographic endothelial dysfunction and increase in the arterial stiffness. An improved understanding of the role in the endothelial system of migraine may provide a basis for preventive drugs in migraine and restore the endothelial function.
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