Evidence map›Paper›PMID 23565340›Full record

ArticleJournal of allergy & therapy2012

The Temporal Evolution of Airways Hyperresponsiveness and Inflammation.

Erik Riesenfeld, Gilman B Allen, Jason Ht Bates, Matthew E Poynter, Min Wu, Steven Aimiand, Lennart Ka Lundblad

Open access · hybridAbstract read
In one paragraph

Article in Journal of allergy & therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Oscillometry of the respiratory system: a translational opportunity not to be missed.American journal of physiology. Lung cellular and molecular physiology · 2021
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.American journal of respiratory cell and molecular biology · 2016
    Article
  7. Dissecting the inflammatory twitch in allergically inflamed mice.American journal of physiology. Lung cellular and molecular physiology · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma.American journal of physiology. Lung cellular and molecular physiology · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Erik RiesenfeldBassett Medical Center, Cooperstown, NY, USA.
Gilman B Allen
Jason Ht Bates
Matthew E Poynter
Min Wu
Steven Aimiand
Lennart Ka Lundblad
Bassett Medical Center · USUniversity of Vermont · US

Funding

WEIGHT LOSS & ASTHMAP20RR015557 · NCRR · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G · 2000 to 2009
$21.4M
Multidisciplinary Training in Lung BiologyT32HL076122 · NHLBI · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI IRVIN, CHARLES G, POYNTER, MATTHEW E · 2004 to 2023
$6.1M
Nitrogen Dioxide in the Sensitization to Allergic Airway DiseaseR01HL089177 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI POYNTER, MATTHEW E · 2007 to 2011
$2.2M
NCRR NIH HHS P20 RR015557NHLBI NIH HHS R01 HL089177NHLBI NIH HHS T32 HL076122
6 · The paper itself

Abstract

Airways hyperresponsiveness (AHR) is usually produced within days of first antigen exposure in mouse models of asthma. Furthermore, continual antigen challenge eventually results in the resolution of the AHR phenotype. Human asthma also waxes and wanes with time, suggesting that studying the time course of AHR in the allergic mouse would offer insights into the variation in symptoms seen in asthmatics. Mice were sensitized with ovalbumin (OVA) on days 0 and 14. As assessed by airway resistance (

Identifiers

PMID23565340
PMCPMC3615437
OpenAlexW2080611631

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.