ArticleFrontiers in microbiology2013
Global Molecular Analyses of Methane Metabolism in Methanotrophic Alphaproteobacterium, Methylosinus trichosporium OB3b. Part I: Transcriptomic Study.
Article in Frontiers in microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 92 citations in OpenAlex.
- Impact of Copper on the Physiology and Transcriptome of Methylosinus Trichosporium OB3b Grown on Either Methane or Methanol.Environmental microbiology · 2026Article
- Non-growth substrate ethane perturbs core methanotrophy in obligate methanotrophApplied and environmental microbiology · 2025Article
- Harnessing the potential of microbial methane utilization for chasing sustainability.Current opinion in biotechnology · 2025Review
- Biofilm Formation on Excavation Damaged Zone Fractures in Deep Neogene Sedimentary Rock.Microbial ecology · 2024Article
- Methane biohydroxylation into methanol byFrontiers in bioengineering and biotechnology · 2024Article
- Comparative genomic analysis of Methylocystis sp. MJC1 as a platform strain for polyhydroxybutyrate biosynthesis.PloS one · 2023Article
- Ecological Aerobic Ammonia and Methane Oxidation Involved Key Metal Compounds, Fe and Cu.Life (Basel, Switzerland) · 2022Review
- Turning C1-gases to isobutanol towards great environmental and economic sustainability via innovative biological routes: two birds with one stone.Biotechnology for biofuels and bioproducts · 2022Article
- RNA Biomarker Trends across Type I and Type II Aerobic Methanotrophs in Response to Methane Oxidation Rates and Transcriptome Response to Short-Term Methane and Oxygen Limitation in Methylomicrobium album BG8.Microbiology spectrum · 2022Article
- Transcriptomic profiling of nitrogen fixation and the role of NifA in Methylomicrobium buryatense 5GB1.Applied microbiology and biotechnology · 2022Article
- Systems Metabolic Engineering of Methanotrophic Bacteria for Biological Conversion of Methane to Value-Added Compounds.Advances in biochemical engineering/biotechnology · 2022Article
- Construction of a tunable promoter library to optimize gene expression in Methylomonas sp. DH-1, a methanotroph, and its application to cadaverine production.Biotechnology for biofuels · 2021Article
- Metal(loid) speciation and transformation by aerobic methanotrophs.Microbiome · 2021Review
- Genome-scale revealing the central metabolic network of the fast growing methanotroph Methylomonas sp. ZR1.World journal of microbiology & biotechnology · 2021Article
- Shifts in Soil Structure, Biological, and Functional Diversity Under Long-Term Carbon Deprivation.Frontiers in microbiology · 2021Article
- Genomic and Physiological Properties of a Facultative Methane-Oxidizing Bacterial Strain ofMicroorganisms · 2020Article
- Economic Perspectives of Biogas Production via Anaerobic Digestion.Bioengineering (Basel, Switzerland) · 2020Article
- Genome-Scale Metabolic Model Reconstruction and in Silico Investigations of Methane Metabolism inMicroorganisms · 2020Article
- Molecular Mechanism Associated With the Impact of Methane/Oxygen Gas Supply Ratios on Cell Growth ofFrontiers in bioengineering and biotechnology · 2020Article
- Biological conversion of propane to 2-propanol using group I and II methanotrophs as biocatalysts.Journal of industrial microbiology & biotechnology · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methane utilizing bacteria (methanotrophs) are important in both environmental and biotechnological applications, due to their ability to convert methane to multicarbon compounds. However, systems-level studies of methane metabolism have not been carried out in methanotrophs. In this work we have integrated genomic and transcriptomic information to provide an overview of central metabolic pathways for methane utilization in Methylosinus trichosporium OB3b, a model alphaproteobacterial methanotroph. Particulate methane monooxygenase, PQQ-dependent methanol dehydrogenase, the H4MPT-pathway, and NAD-dependent formate dehydrogenase are involved in methane oxidation to CO2. All genes essential for operation of the serine cycle, the ethylmalonyl-CoA (EMC) pathway, and the citric acid (TCA) cycle were expressed. PEP-pyruvate-oxaloacetate interconversions may have a function in regulation and balancing carbon between the serine cycle and the EMC pathway. A set of transaminases may contribute to carbon partitioning between the pathways. Metabolic pathways for acquisition and/or assimilation of nitrogen and iron are discussed.
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