ArticleFrontiers in human neuroscience2013
Anatomy and computational modeling of networks underlying cognitive-emotional interaction.
Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed.
- Emotional Context Modulates Neural Prediction-Error Encoding.Psychophysiology · 2026Article
- Computational modeling of fear and stress responses: validation using consolidated fear and stress protocols.Frontiers in systems neuroscience · 2024Article
- Sleep spindles in primates: Modeling the effects of distinct laminar thalamocortical connectivity in core, matrix, and reticular thalamic circuits.Network neuroscience (Cambridge, Mass.) · 2023Article
- Pathways for Memory, Cognition and Emotional Context: Hippocampal, Subgenual Area 25, and Amygdalar Axons Show Unique Interactions in the Primate Thalamic Reuniens Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- The prefrontal cortex, pathological anxiety, and anxiety disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Neural Circuits Underlying Social Fear in Rodents: An Integrative Computational Model.Frontiers in systems neuroscience · 2022Article
- Stronger functional network connectivity and social support buffer against negative affect during the COVID-19 outbreak and after the pandemic peak.Neurobiology of stress · 2021Article
- Distribution and overlap of entorhinal, premotor, and amygdalar connections in the monkey anterior cingulate cortex.The Journal of comparative neurology · 2021Article
- Imbalance of laminar-specific excitatory and inhibitory circuits of the orbitofrontal cortex in autism.Molecular autism · 2020Article
- A Computational Model Integrating Multiple Phenomena on Cued Fear Conditioning, Extinction, and Reinstatement.Frontiers in systems neuroscience · 2020Article
- Expression and Function of Neuron-Glia-Related Cell Adhesion Molecule (NrCAM) in the Amygdalar Pathway.Frontiers in cell and developmental biology · 2019Article
- Interplay of prefrontal cortex and amygdala during extinction of drug seeking.Brain structure & function · 2018Article
- Mirror trends of plasticity and stability indicators in primate prefrontal cortex.The European journal of neuroscience · 2017Article
- Anterior Cingulate Pathways May Affect Emotions Through Orbitofrontal Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Rapid-Response Impulsivity Predicts Depression and Posttraumatic Stress Disorder Symptomatology at 1-Year Follow-Up in Blast-Exposed Service Members.Archives of physical medicine and rehabilitation · 2017Article
- Posterior Orbitofrontal and Anterior Cingulate Pathways to the Amygdala Target Inhibitory and Excitatory Systems with Opposite Functions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Extraversion and neuroticism related to the resting-state effective connectivity of amygdala.Scientific reports · 2016Article
- The intercalated nuclear complex of the primate amygdala.Neuroscience · 2016Article
- The Emotional Gatekeeper: A Computational Model of Attentional Selection and Suppression through the Pathway from the Amygdala to the Inhibitory Thalamic Reticular Nucleus.PLoS computational biology · 2016Article
- Comparing Volume Loss in Neuroanatomical Regions of Emotion versus Regions of Cognition in Healthy Aging.PloS one · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The classical dichotomy between cognition and emotion equated the first with rationality or logic and the second with irrational behaviors. The idea that cognition and emotion are separable, antagonistic forces competing for dominance of mind has been hard to displace despite abundant evidence to the contrary. For instance, it is now known that a pathological absence of emotion leads to profound impairment of decision making. Behavioral observations of this kind are corroborated at the mechanistic level: neuroanatomical studies reveal that brain areas typically described as underlying either cognitive or emotional processes are linked in ways that imply complex interactions that do not resemble a simple mutual antagonism. Instead, physiological studies and network simulations suggest that top-down signals from prefrontal cortex realize "cognitive control" in part by either suppressing or promoting emotional responses controlled by the amygdala, in a way that facilitates adaptation to changing task demands. Behavioral, anatomical, and physiological data suggest that emotion and cognition are equal partners in enabling a continuum or matrix of flexible behaviors that are subserved by multiple brain regions acting in concert. Here we focus on neuroanatomical data that highlight circuitry that structures cognitive-emotional interactions by directly or indirectly linking prefrontal areas with the amygdala. We also present an initial computational circuit model, based on anatomical, physiological, and behavioral data to explicitly frame the learning and performance mechanisms by which cognition and emotion interact to achieve flexible behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.