ArticleFrontiers in neuroscience2013
The corpulent phenotype-how the brain maximizes survival in stressful environments.
Article in Frontiers in neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Coping Strategies Influence Cardiometabolic Risk Factors in Chronic Psychological Stress: A Post Hoc Analysis of A Randomized Pilot Study.Nutrients · 2021Trial
- How Stress Can Change Our Deepest Preferences: Stress Habituation Explained Using the Free Energy Principle.Frontiers in psychology · 2022Review
- Brain Size, Metabolism, and Social Evolution.Frontiers in physiology · 2021Article
- Impaired Gastric Myoelectrical Reactivity in Children and Adolescents with Obesity Compared to Normal-Weight Controls.Nutrients · 2018Article
- Biological and psychological predictors of posttraumatic stress disorder onset and chronicity. A one-year prospective study.Neurobiology of stress · 2016Article
- Use of medical services and medicines attributable to diabetes in Sub-Saharan Africa.PloS one · 2014Article
- 6(th) Annual Symposium on Self-Monitoring of Blood Glucose (SMBG) applications and beyond, April 25-27, 2013, Riga, Latvia.Diabetes technology & therapeutics · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reactivity of the stress system may change during the life course. In many-but not all-humans the stress reactivity decreases, once the individual is chronically exposed to a stressful and unsafe environment (e.g., poverty, work with high demands, unhappy martial relationship). Such an adaptation is referred to as habituation. Stress habituation allows alleviating the burden of chronic stress, particularly cardiovascular morbidity and mortality. Interestingly, two recent experiments demonstrated low stress reactivity during a mental or psychosocial challenge in subjects with a high body mass. In this focused review we attempt to integrate these experimental findings in a larger context. Are these data compatible with data sets showing a prolonged life expectancy in corpulent people? From the perspective of neuroenergetics, we here raise the question whether "obesity" is unhealthy at all. Is the corpulent phenotype possibly the result of "adaptive phenotypic plasticity" allowing optimized survival in stressful environments?
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.