Evidence map›Paper›PMID 23564631›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Formative evaluation of the accuracy of a clinical decision support system for cervical cancer screening.

Kavishwar Balwant Wagholikar, Kathy L MacLaughlin, Thomas M Kastner, Petra M Casey, Michael Henry, Robert A Greenes, Hongfang Liu, Rajeev Chaudhry

Abstract readEvaluation Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping of Crowdsourcing in Health: Systematic Review.Journal of medical Internet research · 2018
    Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Combining text mining with clinical decision support in clinical practice: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Medical knowledge infused convolutional neural networks for cohort selection in clinical trials.Journal of the American Medical Informatics Association : JAMIA · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Test Case Selection in Pre-Deployment Testing of Complex Clinical Decision Support Systems.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016
    Article
  18. Article
  19. Granular Quality Reporting for Cervical Cytology Testing.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2015
    Article
  20. "Big data" and the electronic health record.Yearbook of medical informatics · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kavishwar Balwant WagholikarDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55901, USA. waghsk@gmail.com
Kathy L MacLaughlin
Thomas M Kastner
Petra M Casey
Michael Henry
Robert A Greenes
Hongfang Liu
Rajeev Chaudhry

Funding

Natural language processing for clinical and translational researchR01GM102282 · NIGMS · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, PAKHOMOV, SERGUEI VS · 2013 to 2016
$2.5M
NIGMS NIH HHS R01 GM102282
6 · The paper itself

Abstract

objectivesWe previously developed and reported on a prototype clinical decision support system (CDSS) for cervical cancer screening. However, the system is complex as it is based on multiple guidelines and free-text processing. Therefore, the system is susceptible to failures. This report describes a formative evaluation of the system, which is a necessary step to ensure deployment readiness of the system. MATERIALS AND

methodsCare providers who are potential end-users of the CDSS were invited to provide their recommendations for a random set of patients that represented diverse decision scenarios. The recommendations of the care providers and those generated by the CDSS were compared. Mismatched recommendations were reviewed by two independent experts.

resultsA total of 25 users participated in this study and provided recommendations for 175 cases. The CDSS had an accuracy of 87% and 12 types of CDSS errors were identified, which were mainly due to deficiencies in the system's guideline rules. When the deficiencies were rectified, the CDSS generated optimal recommendations for all failure cases, except one with incomplete documentation. DISCUSSION AND

conclusionsThe crowd-sourcing approach for construction of the reference set, coupled with the expert review of mismatched recommendations, facilitated an effective evaluation and enhancement of the system, by identifying decision scenarios that were missed by the system's developers. The described methodology will be useful for other researchers who seek rapidly to evaluate and enhance the deployment readiness of complex decision support systems.

Indexed as

Decision Support Systems, ClinicalData MiningEarly Detection of CancerElectronic Health RecordsFemaleHumansNatural Language ProcessingPractice Guidelines as TopicUterine Cervical NeoplasmsCrowdsourcingDecision Support Systems, ClinicalGuideline AdherenceUterine Cervical NeoplasmsVaginal SmearsValidation Studies as Topic

Identifiers

PMID23564631
PMCPMC3721177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.