ArticlePlant physiology2013
A Common histone modification code on C4 genes in maize and its conservation in Sorghum and Setaria italica.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 52 citations in OpenAlex.
- Multi-dimensional epigenomic dynamics converge on H3K4-mediated regulation of low-COPlant communications · 2025Article
- Investigating theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genomic and Transcriptomic Insights into the Evolution of C4 Photosynthesis in Grasses.Genome biology and evolution · 2024Article
- Investigating thebioRxiv : the preprint server for biology · 2024Article
- C4 Phosphoenolpyruvate Carboxylase: Evolution and transcriptional regulation.Genetics and molecular biology · 2024Article
- Compartmentation of photosynthesis gene expression in C4 maize depends on time of day.Plant physiology · 2023Article
- Performance and Genetic Parameters of Poplar Hybrids and Clones in a Field Trial Are Modified by Contrasting Environmental Conditions during the Vegetative Propagation Phase.Plants (Basel, Switzerland) · 2022Article
- Article
- Network and epigenetic characterization of subsets of genes specifically expressed in maize bundle sheath cells.Computational and structural biotechnology journal · 2022Article
- Evolution analysis ofPeerJ · 2022Article
- Targeted misexpression of NAC052, acting in H3K4 demethylation, alters leaf morphological and anatomical traits in Arabidopsis thaliana.Journal of experimental botany · 2020Article
- Genome-wide identification of histone methylation (H3K9BMC genomics · 2019Article
- The effect of AP-2δ on transcription of the Prestin gene in HEI-OC1 cells upon oxidative stress.Cellular & molecular biology letters · 2019Article
- 3-Hydroxyisobutyrate Dehydrogenase Is Involved in Both, Valine and Isoleucine Degradation inPlant physiology · 2017Article
- Plant Carbonic Anhydrases: Structures, Locations, Evolution, and Physiological Roles.Molecular plant · 2017Review
- Histone Acetylation Modifications Affect Tissue-Dependent Expression of Poplar Homologs of CFrontiers in plant science · 2017Article
- A MEM1-like motif directs mesophyll cell-specific expression of the gene encoding the C4 carbonic anhydrase in Flaveria.Journal of experimental botany · 2017Article
- Systems analysis of cis-regulatory motifs in C4 photosynthesis genes using maize and rice leaf transcriptomic data during a process of de-etiolation.Journal of experimental botany · 2016Article
- Analysis of gene expression and histone modification between C4 and non-C4 homologous genes of PPDK and PCK in maize.Photosynthesis research · 2016Article
- An Untranslated cis-Element Regulates the Accumulation of Multiple C4 Enzymes in Gynandropsis gynandra Mesophyll Cells.The Plant cell · 2016Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
C4 photosynthesis evolved more than 60 times independently in different plant lineages. Each time, multiple genes were recruited into C4 metabolism. The corresponding promoters acquired new regulatory features such as high expression, light induction, or cell type-specific expression in mesophyll or bundle sheath cells. We have previously shown that histone modifications contribute to the regulation of the model C4 phosphoenolpyruvate carboxylase (C4-Pepc) promoter in maize (Zea mays). We here tested the light- and cell type-specific responses of three selected histone acetylations and two histone methylations on five additional C4 genes (C4-Ca, C4-Ppdk, C4-Me, C4-Pepck, and C4-RbcS2) in maize. Histone acetylation and nucleosome occupancy assays indicated extended promoter regions with regulatory upstream regions more than 1,000 bp from the transcription initiation site for most of these genes. Despite any detectable homology of the promoters on the primary sequence level, histone modification patterns were highly coregulated. Specifically, H3K9ac was regulated by illumination, whereas H3K4me3 was regulated in a cell type-specific manner. We further compared histone modifications on the C4-Pepc and C4-Me genes from maize and the homologous genes from sorghum (Sorghum bicolor) and Setaria italica. Whereas sorghum and maize share a common C4 origin, C4 metabolism evolved independently in S. italica. The distribution of histone modifications over the promoters differed between the species, but differential regulation of light-induced histone acetylation and cell type-specific histone methylation were evident in all three species. We propose that a preexisting histone code was recruited into C4 promoter control during the evolution of C4 metabolism.
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