ArticleGenome biology and evolution2013
Growth temperature and genome size in bacteria are negatively correlated, suggesting genomic streamlining during thermal adaptation.
Article in Genome biology and evolution, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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102 citing papers in PubMed.
- Genome-wide comparative analysis reveals distinct evolutionary patterns of overlapping genes in prokaryotes and eukaryotes.Heredity · 2026Article
- Genomic characteristics and geographical distribution of uncultivated soil prokaryotes.BMC genomics · 2026Article
- The Maximum Growth Temperature for Eukaryotes Is Thermodynamically Driven but Ecologically Contingent.Life (Basel, Switzerland) · 2026Article
- Article
- Temperature-driven metabolic adaptation in thermophilic microbial communities of Western Sichuan hot springs.BMC microbiology · 2026Article
- Constructing a "periodic table" of bacteria to map diversity in trait space.The ISME journal · 2026Article
- Genomic adaptation strategies to habitat switching in Korarchaeota.Science advances · 2026Article
- Ecological constraints and evolutionary trade-offs shape nitrogen fixation across habitats.ISME communications · 2026Article
- Root microbiome dynamics favor slow-growth strategies duringISME communications · 2026Article
- Nitrogen-fixing microbes gain genes in diverse types of living environments.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Metabolic activity and survival strategies of thermophilic microbiomes during hyperthermophilic composting.mSystems · 2025Article
- Activation energies of both constructive and destructive cellular biochemistry determine maximum growth temperature in archaea.Communications biology · 2025Article
- Phylogenomic Analyses Reveal that Panguiarchaeum Is a Clade of Genome-Reduced Asgard Archaea Within the Njordarchaeia.Molecular biology and evolution · 2025Article
- Review
- Genomic and metabolic network properties in thermophiles and psychrophiles compared to mesophiles.Scientific reports · 2025Article
- Diversification, niche adaptation, and evolution of a candidate phylum thriving in the deep Critical Zone.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Intraspecific divergence withinProceedings. Biological sciences · 2025Article
- Article
- Bacterial Growth Temperature as a Horizontally Acquired Polygenic Trait.Genome biology and evolution · 2025Article
- Land conversion to cropland homogenizes variation in soil biota, gene assemblages, and ecological strategies on local and regional scales.The ISME journal · 2025Article
42 more citing papers are in PubMed but not listed here.
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Abstract
Prokaryotic genomes are small and compact. Either this feature is caused by neutral evolution or by natural selection favoring small genomes-genome streamlining. Three separate prior lines of evidence argue against streamlining for most prokaryotes. We find that the same three lines of evidence argue for streamlining in the genomes of thermophile bacteria. Specifically, with increasing habitat temperature and decreasing genome size, the proportion of genomic DNA in intergenic regions decreases. Furthermore, with increasing habitat temperature, generation time decreases. Genome-wide selective constraints do not decrease as in the reduced genomes of host-associated species. Reduced habitat variability is not a likely explanation for the smaller genomes of thermophiles. Genome size may be an indirect target of selection due to its association with cell volume. We use metabolic modeling to demonstrate that known changes in cell structure and physiology at high temperature can provide a selective advantage to reduce cell volume at high temperatures.
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