Evidence map›Paper›PMID 23563598›Full record

ArticleBehavior genetics2013

Genetic architecture of olfactory behavior in Drosophila melanogaster: differences and similarities across development.

N J Lavagnino, G H Arya, A Korovaichuk, J J Fanara

Abstract read
In one paragraph

Article in Behavior genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

N J LavagninoDepartamento de Ecología, Genética y Evolución, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, 1428, Buenos Aires, Argentina. nlavagnino@ege.fcen.uba.ar
G H Arya
A Korovaichuk
J J Fanara

Funding

Molecular Genetics of Olfaction in DrosophiliaR01GM059469 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI ANHOLT, ROBERT R. H, MACKAY, TRUDY F. · 1999 to 2016
$5.8M
Molecular Genetics of Olfaction in DrosophilaR03TW007070 · FIC · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI ANHOLT, ROBERT R. H · 2005 to 2007
$104k
FIC NIH HHS R03 TW007070FIC NIH HHS TW 007070NIGMS NIH HHS R01 GM059469
6 · The paper itself

Abstract

In the holometabolous insect Drosophila melanogaster, genetic, physiological and anatomical aspects of olfaction are well known in the adult stage, while larval stages olfactory behavior has received some attention it has been less studied than its adult counterpart. Most of these studies focus on olfactory receptor (Or) genes that produce peripheral odor recognition. In this paper, through a loss-of-function screen using P-element inserted lines and also by means of expression analyses of larval olfaction candidate genes, we extended the uncovering of the genetic underpinnings of D. melanogaster larval olfactory behavior by demonstrating that larval olfactory behavior is, in addition to Or genes, orchestrated by numerous genes with diverse functions. Also, our results point out that the genetic architecture of olfactory behavior in D. melanogaster presents a dynamic and changing organization across environments and ontogeny.

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsDNA Mutational AnalysisDrosophila melanogasterGene Expression ProfilingGenes, InsectHomozygoteLarvaMutagenesisOlfactory Receptor NeuronsSmellTime Factors

Identifiers

PMID23563598
PMCPMC3691330

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.