Evidence map›Paper›PMID 23563257›Full record

ArticleThe Science of the total environment2013

Cluster analysis of social and environment inequalities of infant mortality. A spatial study in small areas revealed by local disease mapping in France.

Cindy M Padilla, Severine Deguen, Benoit Lalloue, Olivier Blanchard, Charles Beaugard, Florence Troude, Denis Zmirou Navier, Verónica M Vieira

Abstract readEvaluation Study
In one paragraph

Article in The Science of the total environment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Infant Mortality Related to NOInternational journal of environmental research and public health · 2020
    Pooled it
  2. Social Inequalities in Exposure to Ambient Air Pollution: A Systematic Review in the WHO European Region.International journal of environmental research and public health · 2019
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Preterm Birth in China Between 2015 and 2016.American journal of public health · 2019
    Article
  11. Premature Adult Death and Equity Impact of a Reduction of NO₂, PMInternational journal of environmental research and public health · 2018
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. A Conceptual Framework for the Assessment of Cumulative Exposure to Air Pollution at a Fine Spatial Scale.International journal of environmental research and public health · 2016
    Article
  18. Article
  19. Article
  20. Data analysis techniques: a tool for cumulative exposure assessment.Journal of exposure science & environmental epidemiology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cindy M PadillaEHESP School of Public Health -Sorbonne Paris Cité - Rennes, France. cindy.padilla@ehesp.fr
Severine Deguen
Benoit Lalloue
Olivier Blanchard
Charles Beaugard
Florence Troude
Denis Zmirou Navier
Verónica M Vieira

Funding

Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MONTI, STEFANO · 1995 to 2019
$46.1M
NIEHS NIH HHS 2P42 ES007381-16A1NIEHS NIH HHS P42 ES007381
6 · The paper itself

Abstract

Mapping spatial distributions of disease occurrence can serve as a useful tool for identifying exposures of public health concern. Infant mortality is an important indicator of the health status of a population. Recent literature suggests that neighborhood deprivation status can modify the effect of air pollution on preterm delivery, a known risk factor for infant mortality. We investigated the effect of neighborhood social deprivation on the association between exposure to ambient air NO2 and infant mortality in the Lille and Lyon metropolitan areas, north and center of France, respectively, between 2002 and 2009. We conducted an ecological study using a neighborhood deprivation index estimated at the French census block from the 2006 census data. Infant mortality data were collected from local councils and geocoded using the address of residence. We generated maps using generalized additive models, smoothing on longitude and latitude while adjusting for covariates. We used permutation tests to examine the overall importance of location in the model and identify areas of increased and decreased risk. The average death rate was 4.2‰ and 4.6‰ live births for the Lille and Lyon metropolitan areas during the period. We found evidence of statistically significant precise clusters of elevated infant mortality for Lille and an east-west gradient of infant mortality risk for Lyon. Exposure to NO2 did not explain the spatial relationship. The Lille MA, socioeconomic deprivation index explained the spatial variation observed. These techniques provide evidence of clusters of significantly elevated infant mortality risk in relation with the neighborhood socioeconomic status. This method could be used for public policy management to determine priority areas for interventions. Moreover, taking into account the relationship between social and environmental exposure may help identify areas with cumulative inequalities.

Indexed as

Environmental ExposureInfant MortalityAir PollutantsCitiesCluster AnalysisFranceGeographyHumansInfantInfant, NewbornModels, TheoreticalNitrous OxideResidence CharacteristicsRisk AdjustmentSocioeconomic FactorsAir PollutantsNitrous Oxide

Identifiers

PMID23563257
PMCPMC4097309

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.