Evidence map›Paper›PMID 23563088›Full record

ReviewCellular & molecular immunology2013

Memory NK cells: why do they reside in the liver?

Xiaojun Jiang, Yonglin Chen, Hui Peng, Zhigang Tian

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Tumor immunotherapy: New aspects of natural killer cells.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2018
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. NK cell trafficking in health and autoimmunity:a comprehensive review.Clinical reviews in allergy & immunology · 2014
    Review
  16. NK cells and virus-related cancers.Critical reviews in oncogenesis · 2014
    Review
  17. Emerging concepts in immunity to hepatitis C virus infection.The Journal of clinical investigation · 2013
    Review
  18. Frontiers in natural killer cell immunology.Cellular & molecular immunology · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaojun JiangHefei National Laboratory for Physical Sciences at Microscale, Hefei, China.
Yonglin Chen
Hui Peng
Zhigang Tian

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune memory is the hallmark of adaptive immunity. However, recent studies have shown that natural killer (NK) cells, key components of the innate immune system, also mediate memory responses in mice and humans. Strikingly, memory NK cells were liver-resident in some models, raising the question as to whether the liver is a special organ for the acquisition of NK cell memory. Here, we review the characteristics of NK cell memory by summarizing recent progress and discuss how the liver may generate both the initiation and the recall phase of memory. We propose that the liver may have unique precursors for memory NK cells, which are developmentally distinct from NK cells derived from bone marrow.

Indexed as

AnimalsAntigensHumansImmunologic MemoryKiller Cells, NaturalLiverModels, ImmunologicalAntigens

Identifiers

PMID23563088
PMCPMC4012773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.