ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2013
Nonsurgical embryo transfer device compared with surgery for embryo transfer in mice.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 32 citations in OpenAlex.
- A scalable embryonic stem cell-based platform for efficient generation of mitochondrial DNA mutant mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Impact of embryo culture and day of embryo transfer on the cardiometabolic health of adult mice†.Biology of reproduction · 2025Article
- Artificial Insemination as a Possible Convenient Tool to Acquire Genome-Edited Mice via In Vivo Fertilization with Engineered Sperm.Biotech (Basel (Switzerland)) · 2024Review
- Inducing Pseudopregnancy in Female Mice Without the Need for Vasectomized Males Prior to Non-Surgical Embryo Transfer or Artificial Insemination.Journal of visualized experiments : JoVE · 2023Article
- Review
- Probing morphological, genetic and metabolomic changes of in vitro embryo development in a microfluidic device.Biotechnology progress · 2021Article
- Male-derived copulatory plugs enhance implantation success in female Mus musculus.Biology of reproduction · 2021Article
- A Nonsurgical Embryo Transfer Technique for Fresh and Cultured Blastocysts in Rats.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Serine protease inhibitor disrupts sperm motility leading to reduced fertility in female mice†.Biology of reproduction · 2020Article
- Media optimization to promote rat embryonic development to the blastocyst stage in vitro.Theriogenology · 2020Article
- A human-based assisted reproduction protocol for the menstruating spiny mouse, Acomys cahirinus.PloS one · 2020Article
- Effect of Predator Stress on the Reproductive Performance of Female Mice After Nonsurgical Embryo Transfer.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- Exogenous growth factors do not affect the development of individually cultured murine embryos.Journal of assisted reproduction and genetics · 2018Article
- Protective Effects of Liquiritigenin against Citrinin-Triggered, Oxidative-Stress-Mediated Apoptosis and Disruption of Embryonic Development in Mouse Blastocysts.International journal of molecular sciences · 2017Article
- Rhein Induces Oxidative Stress and Apoptosis in Mouse Blastocysts and Has Immunotoxic Effects during Embryonic Development.International journal of molecular sciences · 2017Article
- Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.Scientific reports · 2016Article
- The cumulative effect of assisted reproduction procedures on placental development and epigenetic perturbations in a mouse model.Human molecular genetics · 2015Article
- A rapid and effective nonsurgical artificial insemination protocol using the NSET™ device for sperm transfer in mice without anesthesia.Transgenic research · 2015Article
- Important aspects of placental-specific gene transfer.Theriogenology · 2014Article
- Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer.Transgenic research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The use of a murine nonsurgical embryo transfer (NSET) device had been described previously for the transfer of blastocysts, morulae, DNA-microinjected embryos, and embryonic stem cell-containing embryos to create genetically modified mice. However, physiologic effects of the NSET device and traditional surgical methods had not been compared directly. Here we used electrocardiography and fecal corticosterone levels to monitor pseudopregnant mice that underwent anesthesia only, the NSET procedure with or without anesthesia, or surgery. These procedures were performed without the use of actual embryos, to focus on effects of the procedures themselves rather than on any physiologic effects due to the deposition of embryos. As compared with surgery and anesthesia, the NSET procedure was associated with less fluctuation in cardiac rhythm and lower levels of the stress biomarker fecal corticosterone. These results indicate that use of the NSET device avoids these physi- ological perturbations as well as other disadvantages of surgery (for example, postoperative pain and need for postoperative analgesia) and therefore provides a valuable refinement of existing mouse embryo transfer procedures.
Indexed as
Identifiers
23562028PMC3548196W1481360686What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.