ArticleComparative medicine2012
Epidemiology and characterization of seizures in a pedigreed baboon colony.
Article in Comparative medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- The Baboon as a Model to Study Human Health and Complex Disease.American journal of primatology · 2026Review
- Diverse species of animal models in epilepsy research: Progress and perspectives.Zoological research · 2025Review
- The upside of epilepsy: Theories of an evolutionary paradox.Epilepsia open · 2025Review
- The Crucial Interplay Between the Lungs, Brain, and Heart to Understand Epilepsy-Linked SUDEP: A Literature Review.Brain sciences · 2025Review
- Automated detection of complex zebrafish seizure behavior at scale.Communications biology · 2025Article
- Genetic Animal Models of Idiopathic Generalized Epilepsies: What Can We Learn from Them?Biomedicines · 2025Review
- Neuroimaging in the Epileptic Baboon.Frontiers in veterinary science · 2022Review
- The baboon in epilepsy research: Revelations and challenges.Epilepsy & behavior : E&B · 2021Review
- Whole Genome Sequence Data From Captive Baboons ImplicateFrontiers in genetics · 2021Article
- Semiology of spontaneous generalized tonic-clonic seizures in the epileptic baboon.Epilepsia open · 2020Article
- Article
- Epilepsy in nonhuman primates.Epilepsia · 2019Review
- Effects of ketamine on EEG in baboons with genetic generalized epilepsy.Epilepsy research · 2019Article
- Analysis of 100 high-coverage genomes from a pedigreed captive baboon colony.Genome research · 2019Article
- A case report of ovotesticular disorder of sex development (OT-DSD) in a baboon (Papio spp.) and a brief review of the non-human primate literature.Journal of medical primatology · 2018Review
- Resting-state functional connectivity changes due to acute and short-term valproic acid administration in the baboon model of GGE.NeuroImage. Clinical · 2017Article
- Voxel-based morphometry in epileptic baboons: Parallels to human juvenile myoclonic epilepsy.Epilepsy research · 2016Article
- Relationship Between Epilepsy and Colpocephaly in Baboons (Papio hamadryas).Comparative medicine · 2016Article
- Cerebrospinal Fluid Levels of Monoamine Metabolites in the Epileptic Baboon.Journal of primatology · 2015Article
- Animal models in epilepsy research: legacies and new directions.Nature neuroscience · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study evaluated the incidence, prevalence, and clinical features of seizures in a pedigreed captive colony of baboons. The association of seizures with subspecies, age, sex, and various clinical features was assessed. Records for 1527 captive, pedigreed baboons were reviewed, and 3389 events were identified in 1098 baboons. Of these events, 1537 (45%) represented witnessed seizures, whereas the remaining 1852 presented with craniofacial trauma or episodic changes in behavior that were suggestive, but not diagnostic, of seizure activity. Seizures were generalized myoclonic or tonic-clonic, with two thirds of the events witnessed in the morning. Seizure onset occurred in adolescence (age, 5 y), with an average of 3 seizures in a lifetime. The incidence and prevalence of seizures were 2.5% and 26%, respectively, whereas the prevalence of recurrent seizures (that is, epilepsy) was 15%. Seizures were more prevalent in male baboons, which tended to present with earlier onset and more seizures over a lifetime than did female baboons. Seizures were equally distributed between the subspecies; age of onset and seizure recurrences did not differ significantly between subspecies. Clinical features including age of onset, characteristics, and diurnal presentation of seizures in baboons suggested similarities to juvenile myoclonic epilepsy in humans. Facial trauma may be useful marker for epilepsy in baboons, but its specificity should be characterized.
Indexed as
Identifiers
23561888PMC3527759W179124863What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.