Evidence map›Paper›PMID 23561681›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2013

Inter-arm blood pressure differences compared with ambulatory monitoring: a manifestation of the 'white-coat' effect?

Una Martin, Roger Holder, James Hodgkinson, Richard McManus

Erratum issuedOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Guideline
  2. Prevalence of systolic inter-arm differences in blood pressure for different primary care populations: systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Pooled it
  3. Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016
    Trial
  4. Article
  5. Article
  6. Observational
  7. A study of the VaSera arterial stiffness device in US patients.Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Article
  8. The interarm blood pressure difference: Do we know enough yet?Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Inter-arm blood pressure differences compare with ambulatory monitoring: a manifestation of the 'white-coat' effect?The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Article
  14. Authors' response.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Una MartinCollege of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. u.martin@bham.ac.uk
Roger Holder
James Hodgkinson
Richard McManus
University of Birmingham · GB

Funding

Department of Health NIHR-RP-02-12-015
6 · The paper itself

Abstract

backgroundInter-arm difference in blood pressure of >10 mmHg is associated with peripheral vascular disease, but it is unclear how much of the difference in sequential right and left arm blood pressure measurements might be due to a 'white-coat' effect.

aimTo use ambulatory blood pressure monitoring (ABPM) to better understand the clinical significance of inter-arm differences in blood pressure. DESIGN AND

settingRetrospective study in a teaching hospital in Birmingham.

methodAnonymised clinical data collected from 784 patients attending a single hospital-based hypertension clinic were retrospectively analysed. Each participant had blood pressure measured sequentially in both arms, followed by ABPM over the subsequent 24 hours.

resultData were available for 710 (91%) patients, of whom 39.3% (279) had a blood pressure difference of 10 mmHg or more between each arm. Compared to daytime systolic ABPM, the difference was 25.1 mmHg using the arm with the highest reading, but only 15.5 mmHg if the lower reading was taken (mean difference 9.6 mmHg (95% confidence interval [CI] = 9.0 mmHg to 10.3 mmHg)). However, differences between mean right (20.7 mmHg) or left (19.9 mmHg) arm blood pressure and daytime systolic ABPM were very similar.

conclusionCompared with ABPM, use of the higher of the left and right arm readings measured sequentially appears to overestimate true mean blood pressure. As there is no significant difference in the extent of disparity with ABPM by left or right arm, this is unlikely to be due to arm dominance and may be due to the 'white-coat' effect reducing blood pressure on repeated measurement. Where a large inter-arm blood pressure difference is detected with sequential measurement, healthcare professionals should re-measure the blood pressure in the original arm.

Indexed as

Age FactorsArmBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsSex FactorsWhite Coat Hypertension

Identifiers

PMID23561681
PMCPMC3553646
OpenAlexW2101277654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.