Evidence map›Paper›PMID 23561230›Full record

Trial reportThe Journal of clinical psychiatry2013

Extreme attributions predict the course of bipolar depression: results from the STEP-BD randomized controlled trial of psychosocial treatment.

Jonathan P Stange, Louisa G Sylvia, Pedro Vieira da Silva Magalhães, David J Miklowitz, Michael W Otto, Ellen Frank, Michael Berk, Andrew A Nierenberg, Thilo Deckersbach

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of clinical psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00012558 (Systematic Treatment Enhancement Program for Bipolar Disorder), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00012558 nacompletednot on this map

Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)

TypeinterventionalSponsorNational Institute of Mental Health (NIMH)Ran1998 to 2005Enrolled5,000ConditionsBipolar DisorderArmslithium, valproate, bupropion, paroxetine, lamotrigine
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Collaborative care approaches for people with severe mental illness.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Inflexibility as a Vulnerability to Depression: A Systematic Qualitative Review.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Extreme attributions predict suicidal ideation and suicide attempts in bipolar disorder: prospective data from STEP-BD.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2014
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jonathan P StangeDepartment of Psychology, Temple University, Philadelphia, Pennsylvania, USA.
Louisa G Sylvia
Pedro Vieira da Silva Magalhães
David J Miklowitz
Michael W Otto
Ellen Frank
Michael Berk
Andrew A Nierenberg
Thilo Deckersbach
Temple University · US

Funding

TREATMENT OF BIPOLAR DISORDER-278980001N01MH080001 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · 1998 to 2003
$5.3M
1/2-Early Intervention for Youth at Risk for Bipolar DisorderR01MH093676 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MIKLOWITZ, DAVID JAY · 2012 to 2016
$3.6M
MAINTENANCE THERAPIES IN BIPOLAR DISORDERSR37MH029618 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FRANK, ELLEN · 1992 to 2002
$3.2M
Cognitive-Behavior Therapy for Bipolar DisorderK23MH074895 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI DECKERSBACH, THILO · 2007 to 2011
$973k
Medical Comorbidity, Medical Burden and Biopolar DisorderR01MH029618 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KUPFER, DAVID J · 1985 to 2006
$262k
Inflexibility and Vulnerability to DepressionF31MH099761 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI STANGE, JONATHAN P · 2012 to 2014
$87k
INTEGRATED FAMILY/INDIVIDUAL THERAPY OF BIPOLAR DISORDERR21MH055101 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI MIKLOWITZ, DAVID JAY · 1996 to 1998
–
FAMILY FACTORS AND OUTCOME IN BIPOLAR DISORDERR29MH043931 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI MIKLOWITZ, DAVID JAY · 1991 to 1995
–
NIMH NIH HHS 1K23MH074895-01A2NIMH NIH HHS F31 MH099761NIMH NIH HHS F31MH099761NIMH NIH HHS K23 MH074895NIMH NIH HHS MH29618NIMH NIH HHS MH43931NIMH NIH HHS MH55101NIMH NIH HHS N01 MH080001NIMH NIH HHS R01 MH029618NIMH NIH HHS R01 MH093676NIMH NIH HHS R37 MH029618
6 · The paper itself

Abstract

objectiveLittle is known about predictors of recovery from bipolar depression or moderators of treatment response. In the present study, we investigated attributional style (a cognitive pattern of explaining the causes of life events) as a predictor of recovery from episodes of bipolar depression and as a moderator of response to psychotherapy for bipolar depression.

method106 depressed outpatients with DSM-IV bipolar I or II disorder who were enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder were randomly assigned to intensive psychotherapy for depression (n = 62) or to collaborative care (n = 44), a minimal psychoeducational intervention. The primary outcome was recovery status at each study visit as measured by the Clinical Monitoring Form. Attributional style was measured at baseline using the Attributional Style Questionnaire. Data were collected between 1998 and 2005.

resultsAll analyses were by intention to treat. Extreme attributions predicted a lower likelihood of recovery (P < .01; OR = 0.93; 95% CI, 0.88-0.98) and longer time until recovery (P < .01; OR = 0.96; 95% CI, 0.93-0.99), independent of the effects of initial depression severity. Among individuals with more pessimistic attributional styles, higher initial depression severity predicted a lower likelihood of recovery (P = .01; OR = 0.64; 95% CI, 0.45-0.91) and longer time until recovery (P < .001; OR = 0.76; 95% CI, 0.66-0.88). There was no difference in recovery rates between intensive psychotherapy and collaborative care (OR = 0.90; 95% CI, 0.40-2.01) in the full sample.

conclusionsThese results suggest that extreme, rigid attributions may be associated with a more severe course of depression and that evaluating attributional style may help clinicians to identify patients who are at risk for experiencing a more severe course of depression.

trial registrationClinicalTrials.gov identifier: NCT00012558.

Indexed as

Bipolar DisorderDepressionAdultCooperative BehaviorDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleMiddle AgedOutcome Assessment, Health CarePatient Education as TopicPredictive Value of TestsPsychiatric Status Rating ScalesPsychological TestsPsychotherapyRisk Assessment

Identifiers

PMID23561230
PMCPMC3646511
OpenAlexW1975080938

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.