ArticleAnatomy & cell biology2013
Gastric stem cells and gastric cancer stem cells.
Article in Anatomy & cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Review
- Gastric epithelial histology and precancerous conditions.World journal of gastrointestinal oncology · 2022Review
- Density of Musashi‑1‑positive stem cells in the stomach of patients with irritable bowel syndrome.Molecular medicine reports · 2020Article
- Gastroprotective effects of nebivolol and simvastatin against cold restraint stress-induced gastric ulcer in rats.Anatomy & cell biology · 2020Article
- Prognostic Prediction Using a Stemness Index-Related Signature in a Cohort of Gastric Cancer.Frontiers in molecular biosciences · 2020Article
- Description of the unusual digestive tract ofPeerJ · 2020Article
- Distinct biological characterization of the CD44 and CD90 phenotypes of cancer stem cells in gastric cancer cell lines.Molecular and cellular biochemistry · 2019Article
- Superficially Spreading Signet-Ring Cell Carcinoma Perpendicularly Colliding with Gastric Adenoma: a Rare Case Report.Journal of gastrointestinal cancer · 2019Article
- Mechanisms of embryonic stomach development.Seminars in cell & developmental biology · 2017Review
- Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44Stem cells translational medicine · 2017Article
- Neuronal Activity in Ontogeny and Oncology.Trends in cancer · 2017Review
- Prognostic values of four Notch receptor mRNA expression in gastric cancer.Scientific reports · 2016Article
- Article
- Current Status on Stem Cells and Cancers of the Gastric Epithelium.International journal of molecular sciences · 2015Review
- Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells.Journal of gastroenterology · 2015Article
- Glioblastoma specific antigens, GD2 and CD90, are not involved in cancer stemness.Anatomy & cell biology · 2015Article
- Interaction of sonic hedgehog (SHH) pathway with cancer stem cell genes in gastric cancer.Medical oncology (Northwood, London, England) · 2015Review
- [Continual self-renewal of the gastric epithelium by cell differentiation: implications for carcinogenesis].Der Pathologe · 2014Article
- Honokiol as a Radiosensitizing Agent for Colorectal cancers.Current colorectal cancer reports · 2013Article
- Expression and significance of Musashi-1 in gastric cancer and precancerous lesions.World journal of gastroenterology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gastric epithelium is continuously regenerated by gastric stem cells, which give rise to various kinds of daughter cells, including parietal cells, chief cells, surface mucous cells, mucous neck cells, and enteroendocrine cells. The self-renewal and differentiation of gastric stem cells need delicate regulation to maintain the normal physiology of the stomach. Recently, it was hypothesized that cancer stem cells drive the cancer growth and metastasis. In contrast to conventional clonal evolution hypothesis, only cancer stem cells can initiate tumor formation, self-renew, and differentiate into various kinds of daughter cells. Because gastric cancer can originate from gastric stem cells and their self-renewal mechanism can be used by gastric cancer stem cells, we review here how critical signaling pathways, including hedgehog, Wnt, Notch, epidermal growth factor, and bone morphogenetic protein signaling, may regulate the self-renewal and differentiation of gastric stem cells and gastric cancer stem cells. In addition, the precancerous change of the gastric epithelium and the status of isolating gastric cancer stem cells from patients are reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.