Evidence map›Paper›PMID 23559821›Full record

ArticleJournal of pharmacy & bioallied sciences2013

Current interventions in the management of knee osteoarthritis.

Dinesh Bhatia, Tatiana Bejarano, Mario Novo

7 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 89 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 3 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03421054 nacompletednot on this mapstarted 2018, after this paper: background citation

Pilot, Open Non-controled Trial to Assess the Feasibility of Implementing Objective Parameters as Primary Endpoints in a Clinical Trial With Patients Affected by Knee Osteoarthritis

TypeinterventionalSponsorRiver Pharma S.r.l.Ran2018 to 2018Enrolled8ConditionsKnee OsteoarthritisArmspatients assuming nutraceutical containing HA
NCT03612986 nacompletednot on this mapstarted 2018, after this paper: background citation

Double Blind, Placebo Controlled Trial to Evaluate the Effects of a Nutraceutical Containing High-Molecular-Weight Hyaluronic Acid (HA) and Acetyl-11-Keto-Beta-Boswellic Acid (AKBA) in Patients Affected by Knee Osteoarthritis

TypeinterventionalSponsorRiver Pharma S.r.l.Ran2018 to 2019Enrolled72ConditionsKnee OsteoarthritisArmsSYALOX® 300 Plus, Placebo
NCT03798002 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of Neuro-muscular Exercise Training Verses Isolated Quadriceps Training Program in Patients With Mild to Moderate Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2019 to 2019Enrolled60ConditionsKnee OsteoarthritisArmsNeuro-muscular exercise training Group, quadriceps training program
NCT04818307 nacompletednot on this mapstarted 2020, after this paper: background citation

Long Term Effects of Mulligan Mobilization With Movement Versus Macquarie Injury Management Group on Function and Pain of Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2020 to 2020Enrolled26ConditionsKnee OsteoarthritisArmsMacquarie Injury Management group, Mulligan Mobilization with Movement
NCT05131048 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effects of Home-based Hip Strengthening Exercises on Pain, Range of Motion and Functional Disability in Knee Osteoarthritis Patients: a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of LahoreRan2021 to 2022Enrolled90ConditionsKnee OsteoarthritisArmsconventional group, experimental group
NCT05222503 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Impact of Sensor Technology in Individuals With Knee OA

TypeinterventionalSponsorOPUM Technologies US LTDRan2021 to 2022Enrolled60ConditionsKnee OsteoarthritisArmsKnee Brace + OPUM Digital Knee, Knee Brace
NCT05657496 phase1 / phase2terminatednot on this mapstarted 2022, after this paper: background citation

Biological Response to Platelet-rich Plasma and Corticosteroid Injections

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2022 to 2025Enrolled23ConditionsKnee OsteoarthritisArmsTriamcinolone Acetonide 40 mg/ml Inj, Susp, Platelet-rich plasma Inj
3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 3 syntheses or guidelines pooled it, 269 citations in OpenAlex.

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  17. Exosome miR-4738-3p-mediated regulation ofBiomolecules & biomedicine · 2024
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dinesh BhatiaDepartment of Biomedical Engineering, Adaptive Neural Systems Laboratory, Miami, Florida, USA.
Tatiana Bejarano
Mario Novo
Florida International University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is progressive joint disease characterized by joint inflammation and a reparative bone response and is one of the top five most disabling conditions that affects more than one-third of persons > 65 years of age, with an average estimation of about 30 million Americans currently affected by this disease. Global estimates reveal more than 100 million people are affected by OA. The financial expenditures for the care of persons with OA are estimated at a total annual national cost estimate of $15.5-$28.6 billion per year. As the number of people >65 years increases, so does the prevalence of OA and the need for cost-effective treatment and care. Developing a treatment strategy which encompasses the underlying physiology of degenerative joint disease is crucial, but it should be considerate to the different age ranges and different population needs. This paper focuses on different exercise and treatment protocols (pharmacological and non-pharmacological), the outcomes of a rehabilitation center, clinician-directed program versus an at home directed individual program to view what parameters are best at reducing pain, increasing functional independence, and reducing cost for persons diagnosed with knee OA.

Indexed as

Arthrocentesishydrotherapymusculoskeletal disordersneuromuscular efficiencyosteoarthritispharmacologicalquadricepsWestern Ontario and McMaster Universities Osteoarthritis Index scale

Identifiers

PMID23559821
PMCPMC3612336
OpenAlexW2040523084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.