Evidence map›Paper›PMID 23558772›Full record

ArticleGenes & development2013

Control of myogenesis by rodent SINE-containing lncRNAs.

Jiashi Wang, Chenguang Gong, Lynne E Maquat

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Long Noncoding RNAs in Taxane Resistance of Breast Cancer.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. LncRNAs at the heart of development and disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Review
  12. Article
  13. Epigenetic Changes and Functions in Pneumoconiosis.Oxidative medicine and cellular longevity · 2022
    Review
  14. Review
  15. Review
  16. Gene regulation by long non-coding RNAs and its biological functions.Nature reviews. Molecular cell biology · 2021
    Review
  17. Article
  18. lncMGPF is a novel positive regulator of muscle growth and regeneration.Journal of cachexia, sarcopenia and muscle · 2020
    Article
  19. Article
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiashi WangDepartment of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA.
Chenguang Gong
Lynne E Maquat
University of Rochester · US

Funding

Regulation of Normal and Defective Human GenesR37GM074593 · NIGMS · UNIVERSITY OF ROCHESTER · PI MAQUAT, LYNNE E · 2014 to 2023
$4.8M
Regulation of Normal and Defective Human GenesR01GM074593 · NIGMS · UNIVERSITY OF ROCHESTER · PI MAQUAT, LYNNE E · 2006 to 2013
$3.1M
NIGMS NIH HHS GM074593NIGMS NIH HHS R01 GM074593NIGMS NIH HHS R37 GM074593
6 · The paper itself

Abstract

Staufen1-mediated mRNA decay (SMD) degrades mRNAs that harbor a Staufen1-binding site (SBS) in their 3' untranslated regions (UTRs). Human SBSs can form by intermolecular base-pairing between a 3' UTR Alu element and an Alu element within a long noncoding RNA (lncRNA) called a ½-sbsRNA. Since Alu elements are confined to primates, it was unclear how SMD occurs in rodents. Here we identify mouse mRNA 3' UTRs and lncRNAs that contain a B1, B2, B4, or identifier (ID) element. We show that SMD occurs in mouse cells via mRNA-lncRNA base-pairing of partially complementary elements and that mouse ½-sbsRNA (m½-sbsRNA)-triggered SMD regulates C2C12 cell myogenesis. Our findings define new roles for lncRNAs as well as B and ID short interspersed elements (SINEs) in mice that undoubtedly influence many developmental and homeostatic pathways.

Indexed as

3' Untranslated RegionsAnimalsBase PairingCell LineMiceMuscle DevelopmentRNA-Binding ProteinsRNA, Long NoncodingRNA, MessengerShort Interspersed Nucleotide ElementsTrans-Activators3' Untranslated RegionsRent1 protein, mouseRNA-Binding ProteinsRNA, Long NoncodingRNA, MessengerStau1 protein, mouseTrans-Activators

Identifiers

PMID23558772
PMCPMC3639419
OpenAlexW2100496115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.