Trial reportMedical science monitor : international medical journal of experimental and clinical research2013
A "patient-tailored" treatment of hypertension with use of impedance cardiography: a randomized, prospective and controlled trial.
Trial report in Medical science monitor : international medical journal of experimental and clinical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03209141 (Impedance Cardiography in the Evaluation of Left Ventricular Diastolic Dysfunction in Patients With Arterial Hypertension Study), which is not on this map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impedance Cardiography in the Evaluation of Left Ventricular Diastolic Dysfunction in Patients With Arterial Hypertension Study (IMPEDDANS)
Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Who benefits more from hemodynamically guided hypotensive therapy? The experience from two randomized, prospective and controlled trials.Therapeutic advances in cardiovascular disease · 2016Trial
- A Retrospective Study to Investigate the Relationship Between Body Mass Index and Hemodynamic Characteristics in Hypertensive Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2025Review
- Finite velocity of ECG signal propagation: preliminary theory, results of a pilot experiment and consequences for medical diagnosis.Scientific reports · 2023Article
- Age- and Gender-Related Differences in the Hemodynamic Status of Patients with Mild or Moderate Hypertension.International journal of general medicine · 2022Article
- Article
- Non-invasive Systemic Hemodynamic Index in Vascular Risk Stratification Tailored for Hypertensives.Frontiers in cardiovascular medicine · 2021Article
- Haemodynamic Effects of Anaemia in Patients with Acute Decompensated Heart Failure.Cardiology research and practice · 2020Article
- Hemodynamic monitoring using thoracic bioimpedance - an optimal solution for the treatment of hypertension.Clujul medical (1957) · 2018Article
- Use of Biomarkers in the Evaluation and Treatment of Hypertensive Patients.Current hypertension reports · 2016Review
- The diagnostic value of supine blood pressure in hypertension.Archives of medical science : AMS · 2016Article
- The hemodynamic patterns in hypertensive men and women of different age.Journal of human hypertension · 2016Article
- Current therapeutic approaches to cardio-protection in hypertension.Current hypertension reports · 2014Review
- Individualizing antihypertensive combination therapies: clinical and hemodynamic considerations.Current hypertension reports · 2014Review
- Ambulatory blood pressure monitoring can unmask hypertension in patients with psoriasis vulgaris.Medical science monitor : international medical journal of experimental and clinical research · 2013Article
- Hemodynamic differences among hypertensive patients with and without heart failure using impedance cardiography.Therapeutic advances in cardiovascular diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArterial hypertension might be caused by hemodynamic disturbances such as fluid retention, increased vascular resistance, and hyperdynamic function of the heart. The aim of this study was to estimate the effectiveness of antihypertensive therapy based on hemodynamic assessment by impedance cardiography in a randomized, prospective, controlled trial. MATERIAL AND
methodsThis study involved 128 patients (average age: 42.9 ± 11.1 years) with arterial hypertension, randomized into groups: (1) empiric, and (2) hemodynamic, in which treatment choice considered impedance cardiography results. Evaluation of treatment effects was performed after 12 weeks and included office blood pressure measurement and ambulatory blood pressure monitoring.
resultsAll final blood pressure values were lower in the hemodynamic group, significantly for office systolic blood pressure (empiric vs. hemodynamic: 136.1 vs. 131.6 mmHg; p=0.036) and diastolic blood pressure (87.0 vs. 83.7 mmHg; p=0.013), as well as night-time systolic blood pressure (121.3 vs. 117.2 mmHg; p=0.023) and diastolic blood pressure (71.9 vs. 68.4 mmHg; p=0.007). Therapy based on impedance cardiography significantly increased the reduction in office systolic blood pressure (11.0 vs. 17.3 mmHg; p=0.008) and diastolic blood pressure (7.7 vs. 12.2 mmHg; p=0.0008); as well as 24-h mean systolic blood pressure (9.8 vs. 14.2 mmHg; p=0.026), daytime systolic blood pressure (10.5 vs. 14.8 mmHg; p=0.040), and night-time systolic blood pressure (7.7 vs. 12.2 mmHg; p=0.032).
conclusionsAntihypertensive treatment based on impedance cardiography can significantly increase blood pressure reduction in hypertensive patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.