Evidence map›Paper›PMID 23558168›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.

Sunghwan Sohn, Kavishwar B Wagholikar, Dingcheng Li, Siddhartha R Jonnalagadda, Cui Tao, Ravikumar Komandur Elayavilli, Hongfang Liu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  3. Extracting Temporal Expressions of First Seizure Onset from Epilepsy Patient Discharge Summaries.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2023
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  5. Temporal disambiguation of relative temporal expressions in clinical texts.Frontiers in research metrics and analytics · 2022
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  11. Article
  12. Article
  13. Extraction of Temporal Information from Clinical Narratives.Journal of healthcare informatics research · 2019
    Article
  14. Review
  15. Achievability to Extract Specific Date Information for Cancer Research.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2019
    Article
  16. Article
  17. Article
  18. Entity recognition from clinical texts via recurrent neural network.BMC medical informatics and decision making · 2017
    Article
  19. Correlating Lab Test Results in Clinical Notes with Structured Lab Data: A Case Study in HbA1c and Glucose.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sunghwan SohnDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
Kavishwar B Wagholikar
Dingcheng Li
Siddhartha R Jonnalagadda
Cui Tao
Ravikumar Komandur Elayavilli
Hongfang Liu
Mayo Clinic · US

Funding

Informatics for Integrating Biology/ the Bedside (RMI)U54LM008748 · NLM · BRIGHAM AND WOMEN'S HOSPITAL · PI KOHANE, ISAAC S. · 2004 to 2013
$39.0M
Natural language processing for clinical and translational researchR01GM102282 · NIGMS · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, PAKHOMOV, SERGUEI VS · 2013 to 2016
$2.5M
Onto-BioThesaurus: ontological representation of gene/protein names for biomedicaR01LM009959 · NLM · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG · 2009 to 2010
$1.2M
Challenges in Natural Language Processing in Clinical TextR13LM011411 · NLM · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI UZUNER, OZLEM · 2012 to 2016
$98k
Improving the Efficiency and Efficacy in Authoring Essential Clinical FAQsK99LM011389 · NLM · MAYO CLINIC ROCHESTER · PI JONNALAGADDA, SIDDHARTHA REDDY · 2012 to 2012
$97k
NIGMS NIH HHS R01 GM102282NLM NIH HHS 1K99LM011389NLM NIH HHS K99 LM011389NLM NIH HHS R01 LM009959NLM NIH HHS R01LM009959A1NLM NIH HHS R13 LM011411NLM NIH HHS U54 LM008748
6 · The paper itself

Abstract

backgroundTemporal information detection systems have been developed by the Mayo Clinic for the 2012 i2b2 Natural Language Processing Challenge.

objectiveTo construct automated systems for EVENT/TIMEX3 extraction and temporal link (TLINK) identification from clinical text. MATERIALS AND

methodsThe i2b2 organizers provided 190 annotated discharge summaries as the training set and 120 discharge summaries as the test set. Our Event system used a conditional random field classifier with a variety of features including lexical information, natural language elements, and medical ontology. The TIMEX3 system employed a rule-based method using regular expression pattern match and systematic reasoning to determine normalized values. The TLINK system employed both rule-based reasoning and machine learning. All three systems were built in an Apache Unstructured Information Management Architecture framework.

resultsOur TIMEX3 system performed the best (F-measure of 0.900, value accuracy 0.731) among the challenge teams. The Event system produced an F-measure of 0.870, and the TLINK system an F-measure of 0.537.

conclusionsOur TIMEX3 system demonstrated good capability of regular expression rules to extract and normalize time information. Event and TLINK machine learning systems required well-defined feature sets to perform well. We could also leverage expert knowledge as part of the machine learning features to further improve TLINK identification performance.

Indexed as

Artificial IntelligenceElectronic Health RecordsNatural Language ProcessingPatient Discharge SummariesHumansInformation Storage and RetrievalTime

Identifiers

PMID23558168
PMCPMC3756269
OpenAlexW2163241422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.