ReviewJournal of molecular and cellular cardiology2013
Channelopathies from mutations in the cardiac sodium channel protein complex.
Review in Journal of molecular and cellular cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- Successful cryoablation for typical atrial flutter in a toddler with sinus node dysfunction: the youngest case report.European heart journal. Case reports · 2026Article
- Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel NaThe Journal of pharmacology and experimental therapeutics · 2023Article
- NaStructure (London, England : 1993) · 2021Article
- Differential Effect of Three Macrolide Antibiotics on Cardiac Pathology and Electrophysiology in a Myocardial Infarction Rat Model: Influence on Sodium Nav1.5 Channel Expression.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Cardiac small-conductance calcium-activated potassium channels in health and disease.Pflugers Archiv : European journal of physiology · 2021Review
- Long QT syndrome - Bench to bedside.Heart rhythm O2 · 2021Article
- Mechanisms of death in structurally normal stillbirths.Journal of perinatal medicine · 2019Observational
- Computational models in cardiology.Nature reviews. Cardiology · 2019Review
- Article
- Small-conductance CaExperimental & molecular medicine · 2018Review
- Sinus Bradycardia in Carriers of the SCN5A-1795insD Mutation: Unraveling the Mechanism through Computer Simulations.International journal of molecular sciences · 2018Article
- Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaBiophysical chemistry · 2017Article
- Azithromycin Causes a Novel Proarrhythmic Syndrome.Circulation. Arrhythmia and electrophysiology · 2017Article
- Molecular Pathophysiology of Congenital Long QT Syndrome.Physiological reviews · 2017Review
- Murine Electrophysiological Models of Cardiac Arrhythmogenesis.Physiological reviews · 2017Review
- Voltage-Gated Na+ Channels: Not Just for Conduction.Cold Spring Harbor perspectives in biology · 2016Review
- IK1-enhanced human-induced pluripotent stem cell-derived cardiomyocytes: an improved cardiomyocyte model to investigate inherited arrhythmia syndromes.American journal of physiology. Heart and circulatory physiology · 2016Article
- A novel mutation in the SCN5A gene contributes to arrhythmogenic characteristics of early repolarization syndrome.International journal of molecular medicine · 2016Article
- Cardiac Sodium Channel Mutations: Why so Many Phenotypes?Current topics in membranes · 2016Article
- Small-conductance Ca2+ -activated K+ channels and cardiac arrhythmias.Heart rhythm · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The cardiac sodium current underlies excitability in heart, and inherited abnormalities of the proteins regulating and conducting this current cause inherited arrhythmia syndromes. This review focuses on inherited mutations in non-pore forming proteins of sodium channel complexes that cause cardiac arrhythmia, and the deduced mechanisms by which they affect function and dysfunction of the cardiac sodium current. Defining the structure and function of these complexes and how they are regulated will contribute to understanding the possible roles for this complex in normal and abnormal physiology and homeostasis. This article is part of a Special Issue entitled "Na(+) Regulation in Cardiac Myocytes".
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.